NA Cancer Research Results

NA, NA: Click to Expand ⟱
Source: NA
Type: NA
NA
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
7768- IBC,    Isobavachalcone Induces ROS-Mediated Apoptosis via Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells
- in-vitro, NA, PC3
NA↑, TrxR1↓, ER Stress↑, TumCP↓, Apoptosis↑, GRP78/BiP↑, ATF4↑, XBP-1↑, CHOP/DDIT3↑, p‑eIF2α↑, eff↓, cl‑Casp3↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

TrxR1↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   cl‑Casp3↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 1,   GRP78/BiP↑, 1,   XBP-1↑, 1,  

Migration(tgid=13) ⓘ

TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↓, 1,  
Total Targets: 12

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: NA, NA
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:0  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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