tumCV Cancer Research Results

tumCV, Cell Viability: Click to Expand ⟱
Source:
Type:
Cell Viability
HCC, Hepatocellular Carcinoma: Click to Expand ⟱
Hepatocellular Carcinoma
Scientific Papers found: Click to Expand⟱
5259- 3BP,    Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
- in-vivo, HCC, NA
ATP↓, TumCD↑, toxicity↓, eff↑, tumCV↓, Dose↝,
5481- BM,    Therapeutic potential of Bacopa monnieri extracts against hepatocellular carcinoma through in-vitro and computational studies
- in-vitro, HCC, HepG2
tumCV↓, Apoptosis↑, TumCP↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, lipid-P↓,
725- Bor,    Boric acid exert anti-cancer effect in poorly differentiated hepatocellular carcinoma cells via inhibition of AKT signaling pathway
- in-vitro, HCC, NA
tumCV↓, Apoptosis↑, TumAuto↑, p‑Akt↓,
5841- CAP,    The red pepper’s spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ
- in-vitro, HCC, HepG2
AMPK↑, CaMKII ↑, tumCV↓, Akt↓, mTOR↓, ROS↑,
5906- CAR,    Screening and Validation of a Carvacrol-Targeting Viability-Regulating Protein, SLC6A3, in Liver Hepatocellular Carcinoma
- in-vitro, HCC, NA
tumCV↓, SLC6A3?,
2820- CUR,    Hepatoprotective Effect of Curcumin on Hepatocellular Carcinoma Through Autophagic and Apoptic Pathways
- in-vitro, HCC, HepG2
*hepatoP↑, *ROS↓, tumCV↓,
7438- CYN,    Cynaropicrin Suppresses Cell Proliferation by Inducing Mitophagy through p38 MAPK-Mediated Mitochondrial ROS Generation in Human Hepatocellular Carcinoma Cells
- in-vitro, HCC, NA
tumCV↓, TumAuto↑, selectivity↑, mt-ROS↑, MMP↓, LC3B↑, Beclin-1/ATG6↓, p62↓, PINK1↑, PARK2↑, eff↓, p‑MAPK↑,
7237- EGb 761,    Ginkgo biloba Extract Mechanism Inhibits Hepatocellular Carcinoma through the Nuclear Factor-κB/p53 Signaling Pathway
- in-vitro, HCC, HepG2
TumCG↓, tumCV↓, Apoptosis↑, P53↑, NF-kB↓,
6385- Eug,    Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms
- in-vivo, HCC, HepG2
tumCV↓, TumCMig↓, *ALAT↓, *AST↓, *ALP↓, *Bil↓, *CEA↓, *lipid-P↓, *TNF-α↓, *IL1β↓, NF-kB↓, CXCR3↓, HRAS↓, KRAS↓, Ki-67↓, *GSH↑, *GPx↑, *SOD↑, *NRF2↑, P53↑, BAX↑, DR4↑, DR5↑,
6427- FEO,    Foeniculum vulgare seed extract exerts anti-cancer effects on hepatocellular carcinoma
- vitro+vivo, HCC, NA
tumCV↓, Apoptosis↑, TumCMig↓, TumCG↓, survivin↓, mtDam↑, Casp3↑,
7264- Gink,    Anti-tumor effect of ginkgetin on human hepatocellular carcinoma cell lines by inducing cell cycle arrest and promoting cell apoptosis
- vitro+vivo, HCC, HepG2 - NA, HCC, SK-HEP-1
tumCV↓, TumCCA↓, Casp3↑, Cyt‑c↑, TumCG↓, Dose↝,
8103- KAE,    The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions
- in-vitro, HCC, HUH7
Dose↝, HIF-1↓, tumCV↓,
8150- lamb,    Reactive oxygen species dependent phosphorylation of the liver kinase B1/AMP activated protein kinase/ acetyl-CoA carboxylase signaling is critically involved in apoptotic effect of lambertianic acid in hepatocellular carcinoma cells
- in-vitro, HCC, HepG2 - in-vitro, HCC, SK-HEP-1
lipidLev↓, TumCCA↑, cl‑Casp3↑, cl‑PARP↑, AMPK↑, Akt↓, mTOR↓, Bcl-2↓, Bcl-xL↓, COX2/PTGS2↓, ROS↑, eff↓, p‑STK11/LKB1↑, p‑ACC↑, *Obesity↓, *Stress↓, *antiAll↑, tumCV↓, selectivity↑, TumCP↓,
5611- NaHCO3,    NaHCO3 enhances the antitumor activities of cytokine-induced killer cells against hepatocellular carcinoma HepG2 cells
- vitro+vivo, HCC, HepG2
tumCV↓, TumCG↓, pH↑, eff↑, Imm↑,
1939- PL,    Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP
- in-vitro, HCC, HepG2 - in-vitro, HCC, HUH7 - in-vivo, NA, NA
TumCMig↓, TumCI↓, ER Stress↑, selectivity↑, tumCV↓, ROS↑, GSH↓, eff↓, Ca+2↑, MAPK↑, CHOP/DDIT3↑, Dose↝,
2418- SK,    Experimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2
- in-vitro, HCC, SMMC-7721 cell - in-vitro, HCC, HUH7 - in-vitro, HCC, HepG2
tumCV↓, GlucoseCon↓, lactateProd↓, ChemoSen↑, PKM2↓, Glycolysis↓,
2110- TQ,    Nigella sativa seed oil suppresses cell proliferation and induces ROS dependent mitochondrial apoptosis through p53 pathway in hepatocellular carcinoma cells
- in-vitro, HCC, HepG2 - in-vitro, BC, MCF7 - in-vitro, Lung, A549 - in-vitro, Nor, HEK293
P53↑, lipid-P↑, GSH↓, ROS↑, MMP↓, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, tumCV↓, selectivity↑,

Showing Research Papers: 1 to 17 of 17

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 17

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

CXCR3↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

GSH↓, 2,   lipid-P↓, 1,   lipid-P↑, 1,   PARK2↑, 1,   ROS↑, 4,   mt-ROS↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   MMP↓, 2,   mtDam↑, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

p‑ACC↑, 1,   AMPK↑, 2,   GlucoseCon↓, 1,   Glycolysis↓, 1,   lactateProd↓, 1,   lipidLev↓, 1,   PKM2↓, 1,   p‑STK11/LKB1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   p‑Akt↓, 1,   Apoptosis↑, 4,   BAX↑, 2,   Bcl-2↓, 2,   Bcl-xL↓, 1,   Casp3↑, 3,   cl‑Casp3↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,   DR4↑, 1,   DR5↑, 1,   MAPK↑, 1,   p‑MAPK↑, 1,   survivin↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 17,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3B↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 3,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HRAS↓, 1,   mTOR↓, 2,   TumCG↓, 4,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   Ki-67↓, 1,   KRAS↓, 1,   MMP2↓, 1,   MMP9↓, 1,   TumCI↓, 2,   TumCMig↓, 4,   TumCP↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

HIF-1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   Imm↑, 1,   NF-kB↓, 2,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   Dose↝, 4,   eff↓, 3,   eff↑, 2,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

Ki-67↓, 1,   KRAS↓, 1,   SLC6A3?, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  
Total Targets: 72

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

antiAll↑, 1,   Stress↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Bil↓, 1,   GPx↑, 1,   GSH↑, 1,   lipid-P↓, 1,   NRF2↑, 1,   ROS↓, 1,   SOD↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Migration(tgid=13) ⓘ

CEA↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL1β↓, 1,   TNF-α↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   Bil↓, 1,   CEA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

hepatoP↑, 1,   Obesity↓, 1,  
Total Targets: 20

Scientific Paper Hit Count for: tumCV, Cell Viability
1 3-bromopyruvate
1 Bacopa monnieri
1 Boron
1 Capsaicin
1 Carvacrol
1 Curcumin
1 Cynaropicrin
1 Ginkgo biloba-EGb 761
1 Eugenol
1 Fennel Oil/Foeniculum vulgare
1 Ginkgetin
1 Kaempferol
1 lambertianic acid
1 Bicarbonate(Sodium)
1 Piperlongumine
1 Shikonin
1 Thymoquinone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:10  Cells:%  prod#:%  Target#:897  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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