TumCMig Cancer Research Results

TumCMig, Tumor cell migration: Click to Expand ⟱
Source:
Type:
Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.


NSCLC, Non-small Cell Lung Cancer: Click to Expand ⟱
Non-small Cell Lung Cancer

Scientific Papers found: Click to Expand⟱
570- ART/DHA,    Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/β-catenin signaling
- vitro+vivo, NSCLC, A549 - vitro+vivo, NSCLC, H1299
TumCCA↑, CSCs↓, TumCI↓, TumCMig↓, TumCG↓, Wnt/(β-catenin)↓, Nanog↓, SOX2↓, OCT4↓, N-cadherin↓, Vim↓, E-cadherin↑,
5540- BBM,    Berbamine Inhibits Cell Proliferation and Migration and Induces Cell Death of Lung Cancer Cells via Regulating c-Maf, PI3K/Akt, and MDM2-P53 Pathways
- vitro+vivo, NSCLC, NA
TumCMig↓, TumCI↓, PI3K↓, Akt↓, MDM2↓, TumCP↓, TumMeta↓,
5180- BBR,    Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth
- in-vitro, NSCLC, NA
TumCMig↓, TumCP↓, Apoptosis↑, TFAP2A↓, hTERT/TERT↓, NF-kB↓, COX2↓, Hif1a↓, VEGF↓, Akt↓, p‑ERK↓, Cyt‑c↑, cl‑Casp↑, cl‑PARP↑, PI3K↓, Akt↓, Raf↓, MEK↓, ERK↓,
4505- GLA,    Gamma linolenic acid suppresses hypoxia-induced proliferation and invasion of non-small cell lung cancer cells by inhibition of HIF1α
- in-vitro, NSCLC, Calu-1
TumCP↓, PCNA↓, Ki-67↓, MCM2↓, Bcl-2↓, BAX↑, cl‑Casp3↑, TumCMig↓, TumCI↓, Hif1a↓, VEGF↓,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics

MEK↓, 1,   Raf↓, 1,  

Cell Death

Akt↓, 3,   Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   cl‑Casp↑, 1,   cl‑Casp3↑, 1,   Cyt‑c↑, 1,   hTERT/TERT↓, 1,   MDM2↓, 1,  

DNA Damage & Repair

cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence

TFAP2A↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

CSCs↓, 1,   ERK↓, 1,   p‑ERK↓, 1,   MCM2↓, 1,   Nanog↓, 1,   OCT4↓, 1,   PI3K↓, 2,   SOX2↓, 1,   TumCG↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration

E-cadherin↑, 1,   Ki-67↓, 1,   N-cadherin↓, 1,   TumCI↓, 3,   TumCMig↓, 4,   TumCP↓, 3,   TumMeta↓, 1,   Vim↓, 1,  

Angiogenesis & Vasculature

Hif1a↓, 2,   VEGF↓, 2,  

Immune & Inflammatory Signaling

COX2↓, 1,   NF-kB↓, 1,  

Clinical Biomarkers

hTERT/TERT↓, 1,   Ki-67↓, 1,  
Total Targets: 39

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TumCMig, Tumor cell migration
1 Artemisinin
1 Berbamine
1 Berberine
1 γ-linolenic acid (Borage Oil)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:19  Cells:%  prod#:%  Target#:326  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

Home Page