ACSL4 Cancer Research Results

ACSL4, Acyl-CoA Synthetase Long-Chain Family Member 4: Click to Expand ⟱
Source:
Type:
ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4) is a protein that plays a crucial role in the regulation of fatty acid metabolism, particularly in the context of cancer.
ACSL4 has been shown to be highly expressed in various types of cancer.
NSCLC, Non-small Cell Lung Cancer: Click to Expand ⟱
Non-small Cell Lung Cancer
Scientific Papers found: Click to Expand⟱
3215- EGCG,    Epigallocatechin gallate modulates ferroptosis through downregulation of tsRNA-13502 in non-small cell lung cancer
- in-vitro, NSCLC, A549 - in-vitro, NSCLC, H1299
TumCP↓, Ki-67↓, GPx4↓, ACSL4↑, Iron↑, MDA↑, ROS↑, Ferroptosis↑, eff↑, NRF2↑, HO-1↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx4↓, 1,   HO-1↑, 1,   Iron↑, 1,   MDA↑, 1,   NRF2↑, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACSL4↑, 1,  

Cell Death ⓘ

Ferroptosis↑, 1,  

Migration ⓘ

Ki-67↓, 1,   TumCP↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  

Clinical Biomarkers ⓘ

Ki-67↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: ACSL4, Acyl-CoA Synthetase Long-Chain Family Member 4
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:19  Cells:%  prod#:%  Target#:867  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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