Thiols Cancer Research Results
Thiols, Thiols: Click to Expand ⟱
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"Thiols" generally refer to compounds containing sulfhydryl (–SH) groups, with glutathione (GSH) being one of the most abundant and well-studied cellular thiols. Thiol groups play essential roles in maintaining redox balance, detoxifying reactive oxygen species (ROS), and modulating protein function via post-translational modifications.
• Elevated levels of glutathione and related thiols have been associated with enhanced resistance to chemotherapy and radiation, as these treatments often work by inducing oxidative damage.
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AML, Acute Myeloid Leukemia: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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in-vitro, |
AML, |
Jurkat |
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in-vitro, |
Nor, |
L929 |
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necrosis↑, Thiols↓, GSH↓, ENO1↓, Zn2+↑, Glycolysis↓, ATP↓, BioAv↓,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSH↓, 1, Thiols↓, 1,
Metal & Cofactor Biology ⓘ
Zn2+↑, 1,
Mitochondria & Bioenergetics ⓘ
ATP↓, 1,
Core Metabolism/Glycolysis ⓘ
ENO1↓, 1, Glycolysis↓, 1,
Cell Death ⓘ
necrosis↑, 1,
Proliferation, Differentiation & Cell State ⓘ
Zn2+↑, 1,
Drug Metabolism & Resistance ⓘ
BioAv↓, 1,
Total Targets: 9
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: Thiols, Thiols
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:2 Cells:% prod#:% Target#:1224 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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