DFF45 Cancer Research Results

DFF45, DNA Fragmentation Factor 45 Gene: Click to Expand ⟱

Source:

Type:

DFF45 was expressed preferably in low-stage neuroblastoma tumors, and to a lesser degree in high-stage neuroblastomas.

AML, Acute Myeloid Leukemia: Click to Expand ⟱

Acute Myeloid Leukemia

Scientific Papers found: Click to Expand⟱

831-

GAR,

CUR,

Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells

in-vitro,

AML,

HL-60

20 microM

9.4uM(Gar), 19.5uM(Cur)

Apoptosis↑, Casp3↑, MMP↓, Cyt‑c↑, proCasp9↑, Bcl-2↓, BAX↑, PARP↓, DNAdam↑, DFF45↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,

Cell Death ⓘ

Apoptosis↑, 1, BAX↑, 1, Bcl-2↓, 1, Casp3↑, 1, proCasp9↑, 1, Cyt‑c↑, 1,

DNA Damage & Repair ⓘ

DFF45↓, 1, DNAdam↑, 1, PARP↓, 1,
Total Targets: 10

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: DFF45, DNA Fragmentation Factor 45 Gene

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells