TumMeta Cancer Research Results

TumMeta, Cancer Metastasis: Click to Expand ⟱
Source:
Type:
Cancer metastasis is the process by which cancer cells spread from the original (primary) tumor to other parts of the body, forming new (secondary) tumors. This occurs when cancer cells invade surrounding tissues, enter the bloodstream or lymphatic system, and travel to distant organs or tissues.


AML, Acute Myeloid Leukemia: Click to Expand ⟱
Acute Myeloid Leukemia

Scientific Papers found: Click to Expand⟱
5634- BCA,    Molecular Mechanisms of Biochanin A in AML Cells: Apoptosis Induction and Pathway-Specific Regulation in U937 and THP-1
- in-vitro, AML, U937 - in-vitro, AML, THP1
Apoptosis↑, Casp7↑, PARP1↑, Bcl-2↓, Myc↓, CHOP↑, P21↑, p62↑, TumCCA↑, TXNIP↑, ROS↑, *antiOx↑, *Inflam↓, *neuroP↑, AntiCan↑, TumCP↓, angioG↓, TumMeta↓, VEGF↓, MMPs↓, tumCV↓, DNAdam↑, CHOP↑, cMyc↓, BioAv↓, Half-Life↓, BioAv↑,
3182- SFN,    Sulforaphane Modulates AQP8-Linked Redox Signalling in Leukemia Cells
- in-vitro, AML, NA
Prx↓, AQPs↓, NOX↓, tumCV↓, AntiCan↑, cardioP↑, neuroP↑, Inflam↓, chemoPv↑, angioG↓, TumMeta↓, selectivity↑, ROS↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

Prx↓, 1,   ROS↓, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis

cMyc↓, 1,  

Cell Death

Apoptosis↑, 1,   Bcl-2↓, 1,   Casp7↑, 1,   Myc↓, 1,  

Transcription & Epigenetics

tumCV↓, 2,  

Protein Folding & ER Stress

CHOP↑, 2,  

Autophagy & Lysosomes

p62↑, 1,  

DNA Damage & Repair

DNAdam↑, 1,   PARP1↑, 1,  

Cell Cycle & Senescence

P21↑, 1,   TumCCA↑, 1,  

Migration

MMPs↓, 1,   TumCP↓, 1,   TumMeta↓, 2,   TXNIP↑, 1,  

Angiogenesis & Vasculature

angioG↓, 2,   VEGF↓, 1,  

Barriers & Transport

AQPs↓, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,  

Cellular Microenvironment

NOX↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   BioAv↑, 1,   Half-Life↓, 1,   selectivity↑, 1,  

Clinical Biomarkers

Myc↓, 1,  

Functional Outcomes

AntiCan↑, 2,   cardioP↑, 1,   chemoPv↑, 1,   neuroP↑, 1,  
Total Targets: 33

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,  

Functional Outcomes

neuroP↑, 1,  
Total Targets: 3

Scientific Paper Hit Count for: TumMeta, Cancer Metastasis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:2  Cells:%  prod#:%  Target#:604  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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