miR-133a-3p Cancer Research Results

miR-133a-3p, miR-133a-3p: Click to Expand ⟱

Source:

Type:

miR-133a-3p is a microRNA that has been implicated in various types of cancer.
Tumor-Suppressive microRNA, Lineage Control, and Metastasis Restraint

Downregulated in:Esophageal ,GC,BC,Lung,Ovarina (low expression=poor prognoisis).

Upregulated in: HCC, RCC (associated with good prognosis).

AML, Acute Myeloid Leukemia: Click to Expand ⟱

Acute Myeloid Leukemia

Scientific Papers found: Click to Expand⟱

5027-

QC,

NRF2 Is Targeted By the Polyphenol Quercetin and Induces Apoptosis, in Part, through up Regulation of Pro Apoptotic Mirs

in-vivo,

AML,

50uM

human xenograft acute myeloid leukemia (AML)

HDAC4↓, NRF2↓, p‑NRF2↓, miR-133a-3p↑, miR-206↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

NRF2↓, 1, p‑NRF2↓, 1,

Proliferation, Differentiation & Cell State ⓘ

HDAC4↓, 1,

Migration ⓘ

miR-133a-3p↑, 1, miR-206↑, 1,
Total Targets: 5

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: miR-133a-3p, miR-133a-3p

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells