Securin Cancer Research Results

Securin, PTTG1: Click to Expand ⟱
Source:
Type:
Securin is a protein encoded by the PTTG1 (pituitary tumor-transforming gene 1) gene and plays a crucial role in cell cycle regulation, notably in sister chromatid separation.
-Elevated levels of securin have been reported in a wide range of cancers.
Ovarian, Ovarian Cancer: Click to Expand ⟱
Ovarian Cancer
Scientific Papers found: Click to Expand⟱
4677- Ash,    Withaferin A (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells
- vitro+vivo, Ovarian, NA
CSCs↓, Securin↓, ALDH1A1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Cycle & Senescence ⓘ

Securin↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ALDH1A1↓, 1,   CSCs↓, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Securin, PTTG1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:20  Cells:%  prod#:%  Target#:1334  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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