miR-21 Cancer Research Results
miR-21, miR-21: Click to Expand ⟱
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miR-21 is often considered an oncogenic microRNA because its overexpression is frequently observed in many cancers. It can promote tumor growth and progression by targeting and downregulating tumor suppressor genes.
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Ovarian, Ovarian Cancer: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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in-vitro, |
Ovarian, |
MDAH-2774 |
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TumCP↓, TumCI↓, TumCMig↓, Apoptosis↑, ROS↑, miR-21↓, miR-130a↓, Casp8∅, Casp10∅, cycD1/CCND1∅, CDK6∅, CDK4∅, FADD∅, DR4∅, DR5∅,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
Cell Death ⓘ
Apoptosis↑, 1, Casp10∅, 1, Casp8∅, 1, DR4∅, 1, DR5∅, 1, FADD∅, 1,
Transcription & Epigenetics ⓘ
miR-21↓, 1,
Cell Cycle & Senescence ⓘ
CDK4∅, 1, cycD1/CCND1∅, 1,
Migration ⓘ
miR-130a↓, 1, TumCI↓, 1, TumCMig↓, 1, TumCP↓, 1,
Hormonal & Nuclear Receptors ⓘ
CDK6∅, 1,
Total Targets: 15
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: miR-21, miR-21
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:20 Cells:% prod#:% Target#:191 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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