KDR/FLK-1 Cancer Research Results

KDR/FLK-1, Kinase insert Domain-Containing Receptor/Fetal Liver Kinase-1: Click to Expand ⟱

Source:

Type: receptor tyrosine kinase

KDR/FLK-1 (Kinase insert Domain-Containing Receptor/Fetal Liver Kinase-1) is a receptor tyrosine kinase that plays a crucial role in angiogenesis, the process of new blood vessel formation.

Ovarian, Ovarian Cancer: Click to Expand ⟱

Ovarian Cancer

Scientific Papers found: Click to Expand⟱

1147-

ART/DHA,

Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1

vitro+vivo,

Ovarian,

HO-8910

0.5-50uM/L

vitro+vivo,

Nor,

HUVECs

angioG↓, TumCG↓, VEGF↓, KDR/FLK-1↓, *toxicity↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,

Angiogenesis & Vasculature ⓘ

angioG↓, 1, KDR/FLK-1↓, 1, VEGF↓, 1,
Total Targets: 4

Pathway results for Effect on Normal Cells:

Functional Outcomes ⓘ

toxicity↓, 1,
Total Targets: 1

Scientific Paper Hit Count for: KDR/FLK-1, Kinase insert Domain-Containing Receptor/Fetal Liver Kinase-1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells