ITGA5 Cancer Research Results

ITGA5, Integrin alpha 5: Click to Expand ⟱
Source:
Type:
ITGA5 (Integrin alpha 5) is a protein that plays a crucial role in cell adhesion, migration, and signaling. It is a transmembrane receptor that interacts with various extracellular matrix proteins, such as fibronectin, to regulate cell behavior.
ITGA5 has been shown to promote tumor growth, invasion, and metastasis by facilitating cell adhesion, migration, and angiogenesis.
ITGA5 is a gene that encodes for the alpha 5 subunit of the integrin alpha 5 beta 1 (α5β1) receptor. Integrins are a family of transmembrane receptors that play a crucial role in cell adhesion, migration, and signaling.
ITGA5 has been found to be overexpressed in various types of tumorsand its expression has been associated with poor prognosis.
Ovarian, Ovarian Cancer: Click to Expand ⟱
Ovarian Cancer
Scientific Papers found: Click to Expand⟱
1714- Lyco,    Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load
- in-vitro, Ovarian, OV-MZ-6 - in-vivo, NA, NA
ChemoSen↑, CA125↓, ITGA5↓, ITGB1↓, MMP9↓, FAK↓, EMT↓, MAPK↓, MMP9↓, antiOx↑, Ki-67↓, MAPK↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,  

Cell Death ⓘ

MAPK↓, 2,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,  

Migration ⓘ

FAK↓, 1,   ITGA5↓, 1,   ITGB1↓, 1,   Ki-67↓, 1,   MMP9↓, 2,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,  

Clinical Biomarkers ⓘ

CA125↓, 1,   Ki-67↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: ITGA5, Integrin alpha 5
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:20  Cells:%  prod#:%  Target#:863  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page