miR-145 Cancer Research Results

miR-145, miR-145: Click to Expand ⟱
Source:
Type: tumor suppressor miRNA
miR-145 has been identified as a tumor suppressor miRNA, and its downregulation has been observed in various types of cancer.
Ovarian, Ovarian Cancer: Click to Expand ⟱
Ovarian Cancer
Scientific Papers found: Click to Expand⟱
2710- BBR,    Berberine inhibits the Warburg effect through TET3/miR-145/HK2 pathways in ovarian cancer cells
- in-vitro, Ovarian, SKOV3
Warburg↓, miR-145↑, HK2↓, TET3↑, Glycolysis↓, PKM2↓, GLUT1↓, LDH↓, PFK2↓, PDK1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

Glycolysis↓, 1,   HK2↓, 1,   LDH↓, 1,   PDK1↓, 1,   PFK2↓, 1,   PKM2↓, 1,   Warburg↓, 1,  

Transcription & Epigenetics ⓘ

miR-145↑, 1,   TET3↑, 1,  

Barriers & Transport ⓘ

GLUT1↓, 1,  

Clinical Biomarkers ⓘ

LDH↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-145, miR-145
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:20  Cells:%  prod#:%  Target#:839  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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