TumCP Cancer Research Results

TumCP, Tumor Cell proliferation: Click to Expand ⟱
Source:
Type:
Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors.
Pca, Prostate Cancer: Click to Expand ⟱
Prostate Cancer: Alterations in genes such as ERG, SPOP, MYC, androgen receptor (AR), and CHD1, drive PCa progression.
TP53 is the most commonly mutated gene in human cancer.
HH↑, GLI-1↑, SHH↑ P53↓
The loss of p53 and/or other tumor suppressor genes, reduced capacity for DNA repair, the dysfunction of telomerase activity, and changes in the pathways that govern the growth of cells also mediate the progression of Pca.
It has been well documented that Ca2+ influx and MDR1 upregulation are highly associated with GEM metabolism in human pancreatic carcinoma.
Increased Growth factor IGF-1/IGF-1R axis activation mediated by both PI3K/Akt or RAF/MEK/ERK system and AR expression remains important in the development and progression of prostate cancer.
It has been demonstrated that prostate cancer cells are relatively sensitive to heat stress.
Long non-coding RNA MALAT1 has been reported as an oncogenic target in multiple types of cancers, including PC.
Scientific Papers found: Click to Expand⟱
4435- AgNPs,  Gluc,    Glucose-Functionalized Silver Nanoparticles as a Potential New Therapy Agent Targeting Hormone-Resistant Prostate Cancer cells
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
selectivity↑, ROS↑, mtDam↑, TumCCA↑, TumCP↓, Apoptosis↑, MMP↓,
6396- ANE,  FEO,    Anethole Inhibits the Proliferation of Human Prostate Cancer Cells via Induction of Cell Cycle Arrest and Apoptosis
- in-vitro, Pca, PC3
TumCP↓, TumCG↓, TumCMig↓, CSCs↓, ROS↑, MPT↑, Casp3↑, Casp9↑, DNAdam↑, cl‑PARP↑, Bax:Bcl2↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, cMyc↓, P21↑, p27/CDKN1B↑, NF-kB↓, eff↑,
4808- ASTX,    Anti-Tumor Effects of Astaxanthin by Inhibition of the Expression of STAT3 in Prostate Cancer
- in-vitro, Pca, DU145 - in-vivo, NA, NA
TumCP↓, STAT3↓, Apoptosis↑, TumCMig↓, TumCI↓,
147- ATG,  EGCG,  CUR,    Increased chemopreventive effect by combining arctigenin, green tea polyphenol and curcumin in prostate and breast cancer cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, MCF7
Bax:Bcl2↑, NF-kB↓, PI3K/Akt↓, STAT3↓, chemoPv↑, TumCP↓, TumCCA↑, TumCMig↓,
2602- Ba,    Downregulation of ZFX is associated with inhibition of prostate cancer progression by baicalein
- in-vitro, Pca, NA - in-vivo, Pca, NA
ZFX↓, TumCP↓,
5653- BNL,    Borneol hinders the proliferation and induces apoptosis through the suppression of reactive oxygen species-mediated JAK1 and STAT-3 signaling in human prostate cancer cells
- in-vitro, Pca, PC3
ROS↑, TumCP↓, cycD1/CCND1↓, cycE1↓, Apoptosis↑, BAX↓, Casp3↑, Bcl-2↓, IL6↓, JAK1↓, STAT3↓,
3512- Bor,    Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake
- in-vitro, Pca, DU145
TumCP↓, eIF2α↑, ATF4↑, ATF6↑, GADD34↑, CHOP/DDIT3↓, GRP78/BiP↑, GRP94↑, Risk↓, *BMD↑, Ca+2↓, *Half-Life↝, IRE1∅, chemoP↑,
3513- Bor,    Boric Acid Activation of eIF2α and Nrf2 Is PERK Dependent: a Mechanism that Explains How Boron Prevents DNA Damage and Enhances Antioxidant Status
- in-vitro, Pca, DU145 - in-vitro, Nor, MEF
NRF2↑, selectivity↑, NQO1↑, GCLC↑, HO-1↑, TumCP↓,
705- Bor,    Boric acid inhibits human prostate cancer cell proliferation
- in-vitro, Pca, DU145 - in-vitro, Pca, LNCaP
TumCP↓,
710- Bor,    Boric acid inhibits stored Ca2+ release in DU-145 prostate cancer cells
- in-vitro, Pca, DU145
NAD↓, TumCP↓, CD38↑, Ca+2↓,
4620- Bor,  BTZ,    Boron Compounds in the Breast Cancer Cells Chemoprevention and Chemotherapy
- Review, Var, NA - Review, Arthritis, NA - Review, Pca, NA
Risk↓, *memory↑, *Dose↑, Risk↓, other↝, *testos↑, other↝, Risk↓, TumCP↓, Apoptosis↑, eff↑,
1449- Bos,  Chemo,    Anti-proliferative, Pro-apoptotic, and Chemosensitizing Potential of 3-Acetyl-11-keto-β-boswellic Acid (AKBA) Against Prostate Cancer Cells
- in-vitro, Pca, PC3
TumCP↓, ChemoSen↑, MMP↝, ROS↝, Apoptosis↑,
145- CA,  CUR,    The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3 - in-vitro, PC, DU145
AR↓, ARE/EpRE↑, TumCP↓, PSA↓,
5867- CA,    Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines
- in-vitro, Pca, DU145 - in-vitro, Liver, Hep3B - in-vitro, AML, K562 - in-vitro, Pca, PC3 - in-vitro, BC, MDA-MB-231
TumCP↓, eff↑, other↝,
5828- CAP,    Capsaicin: a novel radio-sensitizing agent for prostate cancer
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, DU145 - in-vitro, Pca, PC3
RadioS↑, NF-kB↓, TumCCA↑, TumCG↓, TumCP↓, DNAdam↑, γH2AX↑, Ki-67↓,
2013- CAP,    Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vivo, NA, NA
TumCP↓, P53↑, P21↑, BAX↑, PSA↓, AR↓, NF-kB↓, Proteasome↓, TumVol↓, eff∅,
5761- CAPE,    Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of AMPK and Akt signaling networks
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vitro, Pca, PC3
TumCP↓, TumCG↓, TumCCA↑, AMPK↓, NF-kB↓, β-catenin/ZEB1↓, CREB↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓,
5940- Cela,    Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway
- in-vivo, Pca, PC3
Dose↝, TumVol↓, TumW↓, angioG↓, VEGF↓, TumCMig↓, TumCP↓, TumCI↓, Akt↓, mTOR↓, P70S6K↓,
1580- Citrate,    Citrate activates autophagic death of prostate cancer cells via downregulation CaMKII/AKT/mTOR pathway
- in-vitro, Pca, PC3 - in-vivo, PC, NA - in-vitro, Pca, LNCaP - in-vitro, Pca, WPMY-1
Apoptosis↑, Ca+2↓, Akt↓, mTOR↓, selectivity↑, TumCP↓, cl‑Casp3↑, cl‑PARP↑, LC3‑Ⅱ/LC3‑Ⅰ↑, p62↓, ATG5↑, ATG7↑, Beclin-1/ATG6↑, TumAuto↑, CaMKII ↓,
461- CUR,    Curcumin inhibits prostate cancer progression by regulating the miR-30a-5p/PCLAF axis
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, miR-30a-5p↑, PCLAF↓, Bcl-2↓, Casp3↓, BAX↑, cl‑Casp3↑,
137- CUR,    Curcumin induces G0/G1 arrest and apoptosis in hormone independent prostate cancer DU-145 cells by down regulating Notch signaling
- in-vitro, Pca, DU145
NOTCH1↓, cycD1/CCND1↓, CDK2↓, P21↑, p27/CDKN1B↑, P53↑, Bcl-2↓, Casp3↑, Casp9↑, TumCCA↑, TumCP↓, Apoptosis↑,
146- CUR,  EGCG,    Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer action in PC3 prostate cancer cells
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
P21↑, TumCCA↑, TumCP↓, BioAv↓,
152- CUR,    Anti-cancer activity of curcumin loaded nanoparticles in prostate cancer
- in-vivo, Pca, NA
β-catenin/ZEB1↓, AR↓, STAT3↓, p‑Akt↓, Mcl-1↓, Bcl-xL↓, cl‑PARP↑, miR-21↓, miR-205↑, TumCG↓, TumCP↓, TumCI↓, angioG↓, TumMeta↓,
133- CUR,    Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3
miR-143↑, PDK1 / PDPK1↓, FOXD3↑, TumCP↓, TumCMig↓, *Inflam↓, *antiOx↑, *chemoPv↑, RadioS↑, ChemoSen↑,
14- CUR,    Curcumin, a Dietary Component, Has Anticancer, Chemosensitization, and Radiosensitization Effects by Down-regulating the MDM2 Oncogene through the PI3K/mTOR/ETS2 Pathway
- vitro+vivo, Pca, PC3
PI3K/mTOR/ETS2↓, MDM2↓, P21↑, Apoptosis↑, TumCP↓, eff↑, RadioS↑,
165- CUR,    Curcumin interrupts the interaction between the androgen receptor and Wnt/β-catenin signaling pathway in LNCaP prostate cancer cells
- in-vitro, Pca, LNCaP
AR↓, β-catenin/ZEB1↓, p‑Akt↓, GSK‐3β↓, p‑β-catenin/ZEB1↑, cycD1/CCND1↓, cMyc↓, chemoPv↑, TumCP↓,
181- CUR,    The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo
- vitro+vivo, Pca, DU145
MMP2↓, MMP9↓, TumCP↓, TumCI↓,
168- CUR,    Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism
- in-vitro, Pca, PC3
Akt↓, mTOR↓, AMPK↑, TAp63α↑, TumCP↓,
6686- DAP,    Lactoferrin-encapsulated dichloroacetophenone (DAP) nanoparticles enhance drug delivery and anti-tumor efficacy in prostate cancer
- in-vivo, Pca, NA
PDK1 / PDPK1↓, TumCP↓, TumCMig↓, BioAv↓, BioAv↑, Apoptosis↑, Casp3↑, Casp7↑, Glycolysis↓,
6277- DL,  docx,    d-Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis
- in-vitro, Pca, DU145 - in-vitro, Nor, PZ-HPV-7
ChemoSen↑, selectivity↑, ROS↑, GSH↓, Casp↑, eff↓, TumCP↓, cl‑Casp9↑, cl‑Casp3↑, P21↑, BAD↑, cl‑PARP↑, Bcl-xL↓, P53↑, mtDam↑, *toxicity↓,
24- EGCG,  GEN,  QC,    Targeting CWR22Rv1 prostate cancer cell proliferation and gene expression by combinations of the phytochemicals EGCG, genistein and quercetin
- in-vitro, Pca, 22Rv1
NQO1↑, P53↑, NQO2↑, chemoPv↑, TumCP↓, AR↓,
7507- FA,    Assessment of the anticancer mechanism of ferulic acid via cell cycle and apoptotic pathways in human prostate cancer cell lines
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3
Dose↝, ATR↑, ATM↑, P21↑, p27/CDKN1B↑, E2F4↑, RB1↑, TP53↑, cycD1/CCND1↓, CDK2↓, CDK4↓, CDK6↓, TumCP↓, Casp1↑, Casp2↑, Casp8↑, Fas↑, TRADD↑, Bcl-2↓, XIAP↓, TumCCA↑,
2499- FBZ,  VitE,    Effects of fenbendazole and vitamin E succinate on the growth and survival of prostate cancer cells
- in-vitro, Pca, PC3
TumCP∅, TumCP↓, toxicity↓, eff↑,
6991- Form,    Formononetin-induced apoptosis of human prostate cancer cells through ERK1/2 mitogen-activated protein kinase inactivation
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3
TumCCA↑, IGF-1↓, PI3K↓, Akt↓, TumCP↓, ERK↓, MAPK↓, BAX↑, Apoptosis↑,
2060- GamB,    Gambogenic acid induces apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells
- in-vitro, Pca, NA
TumCP↓, TumAuto↑, eff↑, ROS↑, ER Stress↑, JNK↑,
1958- GamB,    Gambogenic acid induces apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells
- in-vitro, Pca, NA - in-vivo, NA, NA
AntiCan↑, TumCP↓, TumAuto↑, eff↑, JNK↑, ROS↑, ER Stress↑, eff↓, TumCG↓,
7138- GI,    6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways
- vitro+vivo, BC, MDA-MB-231 - in-vitro, Pca, DU145 - in-vitro, Liver, HepG2 - in-vitro, Lung, A549
TumCP↓, TumMeta↓, p‑STAT3↓, JAK2↓, cSrc↓, JNK↑, p38↑, ERK↑, eff↓, ROS↑, cl‑PARP↑, TumCCA↑, Casp8↑, Casp9↑, Casp3↑, eff↑, Bcl-2↑, Bcl-xL↓, survivin↓, MMP9↓, COX2/PTGS2↓, IAP1↓, Dose?,
7542- HT,    Hydroxytyrosol Induces Apoptosis and Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, C4-2B - in-vitro, Nor, RWPE-1
TumCP↓, selectivity↑, TumCCA↑, cycD1/CCND1↓, CDK2↓, CDK4↓, Apoptosis↑, Casp↑, cl‑PARP↑, Bax:Bcl2↑, tumCV↓, Akt↓, STAT3↓, NF-kB↓, AR↓, ROS↑, mtDam↑, BioAv↓, toxicity↓, eff↑,
4637- HT,    Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells
- in-vitro, Nor, RWPE-1 - in-vitro, Pca, LNCaP - in-vitro, Pca, 22Rv1 - in-vitro, Pca, PC3
selectivity↑, TumCMig↓, p‑Akt↓, ROS↑, CSCs↓, CD44↓, TumCP↓,
4639- HT,    Hydroxytyrosol Induces Apoptosis, Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, C4-2B
TumCP↓, selectivity↑, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, P21↑, p27/CDKN1B↑, Apoptosis↑, Casp↑, cl‑PARP↑, Bax:Bcl2↑, p‑Akt↓, p‑STAT3↓, NF-kB↓, AR↓, ROS↑, *BioAv↓, *toxicity∅,
7688- iod,  CEL,    Iodine prevents the increase of testosterone-induced oxidative stress in a model of rat prostatic hyperplasia
- in-vivo, Pca, NA
TumCP↓, ROS↓, NOS2↓, COX2/PTGS2↓,
7716- IP6,    Inositol hexaphosphate (IP6): a novel treatment for pancreatic cancer
- in-vitro, Pca, MIA PaCa-2 - in-vitro, PC, PANC1
TumCP↓, Apoptosis↑,
7717- IP6,    In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor
- in-vivo, Pca, DU145
TumCG↓, IGFBP3↑, VEGF↓, TumCP↓, angioG↓,
7712- IP6,    Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice
- in-vivo, Pca, NA
toxicity↓, PCNA↓, TumCG↓, TumCP↓, Apoptosis↑, Risk↓,
7691- IP6,    Inositol Hexaphosphate Suppresses Growth and Induces Apoptosis in Prostate Carcinoma Cells in Culture and Nude Mouse Xenograft: PI3K-Akt Pathway as Potential Target
- vitro+vivo, Pca, PC3 - in-vitro, Pca, C4-2B
TumCP↓, Apoptosis↑, Casp3↑, cl‑PARP↑, Akt↓, PI3K↓, p‑GSK‐3β↓, cycD1/CCND1↓, TumVol↓, TumW↓, PCNA↓, angioG↓, CD31/PECAM-1↓, ILK↓, VEGF↓, eNOS↓, Hif1a↓,
7994- itraC,    From fungus fighter to cancer slayer: itraconazole as a multifaceted candidate for drug-resistant prostate cancer
- Review, Pca, NA
HH↓, Gli1↓, TumCP↓, TumCI↓, eff↑,
7963- JG,    Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, DU145
Pin1↓, TumCP↓, TumVol↓, other↝,
8076- KAE,    Kaempferol suppresses prostate cancer metastasis and tumor angiogenesis via disrupting the LIMK1/Cofilin pathway
- in-vivo, Pca, NA
AntiTum↑, TumCP↓, TumCCA↑, VEGF↓, CDK4↓, CDK6↓, LIMK1↓, Cofilin↓, angioG↓,
8191- LGE,    Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells
- in-vitro, Pca, DU145
AntiTum↑, tumCV↓, TumCP↓, ROS?, TumCCA?, selectivity↑,
6481- LIN,    Linalool inhibits 22Rv1 prostate cancer cell proliferation and induces apoptosis
- in-vivo, Pca, 22Rv1
TumCP↓, Apoptosis↑, Ki-67↓, PCNA↓, TumCCA↑, MMP↓, TumCG↓,

Showing Research Papers: 1 to 50 of 73
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 73

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

E2F4↑, 1,   ILK↓, 1,   LIMK1↓, 1,   TRADD↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

ARE/EpRE↑, 1,   GCLC↑, 1,   GSH↓, 1,   HO-1↑, 1,   NQO1↑, 2,   NRF2↑, 1,   ROS?, 1,   ROS↓, 1,   ROS↑, 10,   ROS↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 2,   MMP↝, 1,   MPT↑, 1,   mtDam↑, 3,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↓, 1,   AMPK↑, 1,   ATG7↑, 1,   cMyc↓, 2,   CREB↓, 1,   Glycolysis↓, 1,   NAD↓, 1,   PDK1 / PDPK1↓, 2,   PI3K/Akt↓, 1,   PI3K/mTOR/ETS2↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 6,   p‑Akt↓, 4,   Apoptosis↑, 17,   BAD↑, 1,   BAX↓, 1,   BAX↑, 3,   Bax:Bcl2↑, 4,   Bcl-2↓, 4,   Bcl-2↑, 1,   Bcl-xL↓, 3,   Casp↑, 3,   Casp1↑, 1,   Casp2↑, 1,   Casp3↓, 1,   Casp3↑, 6,   cl‑Casp3↑, 3,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 3,   cl‑Casp9↑, 1,   Fas↑, 1,   GADD34↑, 1,   IAP1↓, 1,   JNK↑, 3,   MAPK↓, 1,   Mcl-1↓, 1,   MDM2↓, 1,   p27/CDKN1B↑, 4,   p38↑, 1,   Proteasome↓, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ↓, 1,   cSrc↓, 1,   FOXD3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

miR-143↑, 1,   miR-205↑, 1,   miR-21↓, 1,   miR-30a-5p↑, 1,   other↝, 4,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   eIF2α↑, 1,   ER Stress↑, 2,   GRP78/BiP↑, 1,   GRP94↑, 1,   IRE1∅, 1,   NQO2↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   p62↓, 1,   TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   ATR↑, 1,   DNAdam↑, 2,   P53↑, 4,   cl‑PARP↑, 8,   PCLAF↓, 1,   PCNA↓, 3,   TP53↑, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 5,   CDK4↓, 6,   cycD1/CCND1↓, 9,   cycE/CCNE↓, 2,   cycE1↓, 1,   P21↑, 8,   RB1↑, 1,   TAp63α↑, 1,   TumCCA?, 1,   TumCCA↑, 14,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 1,   CSCs↓, 2,   ERK↓, 1,   ERK↑, 1,   Gli1↓, 1,   GSK‐3β↓, 1,   p‑GSK‐3β↓, 1,   HH↓, 1,   IGF-1↓, 1,   IGFBP3↑, 1,   mTOR↓, 3,   NOTCH1↓, 1,   P70S6K↓, 1,   PI3K↓, 2,   STAT3↓, 5,   p‑STAT3↓, 2,   TumCG↓, 8,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↓, 3,   CD31/PECAM-1↓, 1,   CD38↑, 1,   Cofilin↓, 1,   Ki-67↓, 2,   MMP2↓, 1,   MMP9↓, 2,   TumCI↓, 6,   TumCMig↓, 8,   TumCP↓, 50,   TumCP∅, 1,   TumMeta↓, 2,   β-catenin/ZEB1↓, 3,   p‑β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 5,   ATF4↑, 1,   eNOS↓, 1,   Hif1a↓, 1,   VEGF↓, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   IL6↓, 1,   JAK1↓, 1,   JAK2↓, 1,   NF-kB↓, 7,   PSA↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 7,   CDK6↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 1,   ChemoSen↑, 3,   Dose?, 1,   Dose↝, 2,   eff↓, 3,   eff↑, 10,   eff∅, 1,   RadioS↑, 3,   selectivity↑, 8,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 7,   IL6↓, 1,   Ki-67↓, 2,   NOS2↓, 1,   PSA↓, 2,   TP53↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 2,   chemoP↑, 1,   chemoPv↑, 3,   Pin1↓, 1,   Risk↓, 5,   toxicity↓, 3,   TumVol↓, 4,   TumW↓, 2,  
Total Targets: 171

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   Dose↑, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BMD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

chemoPv↑, 1,   memory↑, 1,   toxicity↓, 1,   toxicity∅, 1,  
Total Targets: 11

Scientific Paper Hit Count for: TumCP, Tumor Cell proliferation
11 Curcumin
7 Quercetin
5 Boron
5 Sulforaphane (mainly Broccoli)
4 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
3 EGCG (Epigallocatechin Gallate)
3 Capsaicin
3 HydroxyTyrosol
2 Arctigenin
2 Carnosic acid
2 Docetaxel
2 Gambogic Acid
2 Selenite (Sodium)
1 Silver-NanoParticles
1 Glucose
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Astaxanthin
1 Baicalein
1 borneol
1 Bortezomib
1 Boswellia (frankincense)
1 Chemotherapy
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Celastrol
1 Citric Acid
1 Dichloroacetophenone(2,2-)
1 D-limonene
1 Genistein (soy isoflavone)
1 Ferulic acid
1 Fenbendazole
1 Vitamin E
1 Formononetin
1 Ginger/6-Shogaol/Gingerol
1 iodine
1 Celecoxib
1 itraconazole
1 Juglone
1 Kaempferol
1 Lemongrass Extract/Citral
1 Linalool
1 Lycopene
1 Phenethyl isothiocyanate
1 Piperine
1 Plumbagin
1 Paclitaxel/Taxol
1 Rosmarinic acid
1 salinomycin
1 diet Plant based
1 Silymarin (Milk Thistle) silibinin
1 Thymoquinone
1 Urolithin
1 VitK3,menadione
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:22  Cells:%  prod#:%  Target#:327  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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