HCAR2 Cancer Research Results
HCAR2, HCAR2/GPR109A: Click to Expand ⟱
RCC, Renal cell Carcinoma: Click to Expand ⟱
Renal cell carcinoma (RCC) is one of the most common malignant tumors of the urinary system, accounting for 80–90% of kidney neoplasms.
The activation of the mTOR pathway has been found in RCC and is correlated with high grade and poor prognostic patient features (41,42).
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Scientific Papers found: Click to Expand⟱
*eff↓, Dose↝, eff↑, HDAC↓, ac‑H3↓, ac‑H4↓, *HCAR2↑, *Inflam↓, *ROS↓, *NRF2↑, *GSH↑, *CLDN1↑, *ZO-1↑, IL1β↓, IL6↓, COX2↓, eff↝, eff↑, other↝,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Transcription & Epigenetics ⓘ
ac‑H3↓, 1, ac‑H4↓, 1, other↝, 1,
Proliferation, Differentiation & Cell State ⓘ
HDAC↓, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, IL1β↓, 1, IL6↓, 1,
Drug Metabolism & Resistance ⓘ
Dose↝, 1, eff↑, 2, eff↝, 1,
Clinical Biomarkers ⓘ
IL6↓, 1,
Total Targets: 11
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
GSH↑, 1, NRF2↑, 1, ROS↓, 1,
Kinase & Signal Transduction ⓘ
HCAR2↑, 1,
Migration ⓘ
CLDN1↑, 1, ZO-1↑, 1,
Immune & Inflammatory Signaling ⓘ
HCAR2↑, 1, Inflam↓, 1,
Drug Metabolism & Resistance ⓘ
eff↓, 1,
Total Targets: 9
Scientific Paper Hit Count for: HCAR2, HCAR2/GPR109A
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:24 Cells:% prod#:% Target#:1457 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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