TumCMig Cancer Research Results

TumCMig, Tumor cell migration: Click to Expand ⟱
Source:
Type:
Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.
GBM, Glioblastoma: Click to Expand ⟱
Glioblastoma is a fast-growing and aggressive brain tumor.
Scientific Papers found: Click to Expand⟱
1157- And,    Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression
- in-vitro, GBM, GBM8401 - in-vitro, GBM, U251
TumCI↓, TumCMig↓, MMP2↓, ERK↝,
2700- BBR,    Cell-specific pattern of berberine pleiotropic effects on different human cell lines
- in-vitro, GBM, U343 - in-vitro, GBM, MIA PaCa-2 - in-vitro, Nor, HDFa
selectivity↑, TumCCA↑, Casp3↑, TumCI↓, TumCMig↓, N-cadherin?, DNMT1↑,
2757- BetA,    Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO-1 Pathways
- in-vitro, GBM, U251
tumCV↓, TumCMig↓, TumCI↓, Apoptosis↑, p‑PI3K↓, p‑Akt↓, Ferroptosis↑, HO-1↑, NRF2↑,
5885- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, toxicity↓, *Inflam↓, AntiDiabetic↑, cardioP↑, neuroP↑, selectivity↑, Apoptosis↑, p‑Cofilin↑, F-actin↓, PI3K↓, Akt↓, MEK↓, MAPK↓,
5912- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, p‑Cofilin↑, RAS↓, MEK↓, MAPK↓, PI3K↓, Akt↓,
4489- Chit,  SeNPs,    Inhibiting Metastasis and Improving Chemosensitivity via Chitosan-Coated Selenium Nanoparticles for Brain Cancer Therapy
- in-vitro, GBM, U87MG
TumCG↓, TumCMig↓, TumCI↓, ChemoSen↑, *BBB↑, eff↑, eff↑, eff↑, selectivity↑, MMP2↓, MMP9↓, EPR↑,
2590- CHr,    Chrysin suppresses proliferation, migration, and invasion in glioblastoma cell lines via mediating the ERK/Nrf2 signaling pathway
- in-vitro, GBM, T98G - in-vitro, GBM, U251 - in-vitro, GBM, U87MG
TumCP↓, TumCMig↓, TumCI↓, NRF2↓, HO-1↓, NADPH↓, ERK↓,
480- CUR,    Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells
- in-vitro, GBM, SNB19
TumCP↓, TumCMig↓, Apoptosis↑, TumCCA↑, NEDD9↓, NOTCH1↓, p‑Akt↓,
2511- H2,    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
- in-vivo, GBM, U87MG
TumCG↓, OS↑, CD133↓, Ki-67↓, angioG↓, Diff↑, TumCMig↓, TumCI↓, Dose↝, BBB↑, mt-ROS↑,
1412- HCA,    Identification of ATP Citrate Lyase as a Positive Regulator of Glycolytic Function in Glioblastomas
- in-vitro, GBM, U87MG - in-vitro, GBM, LN229
ACLY↓, TumCMig↓,
1153- HNK,    Honokiol Eliminates Glioma/Glioblastoma Stem Cell-Like Cells via JAK-STAT3 Signaling and Inhibits Tumor Progression by Targeting Epidermal Growth Factor Receptor
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG - in-vivo, NA, NA
tumCV↓, Apoptosis↑, TumCMig↓, TumCI↓, Bcl-2↓, EGFR↓, CD133↓, Nestin↓, Akt↓, ERK↓, Casp3↑, p‑STAT3↓, TumCG↓,
516- MFrot,  immuno,  MF,    Anti-tumor effect of innovative tumor treatment device OM-100 through enhancing anti-PD-1 immunotherapy in glioblastoma growth
- vitro+vivo, GBM, U87MG
TumCP↓, Apoptosis↑, TumCMig↓, ROS↑, PD-L1↑, TumVol↓, eff↑, *toxicity∅, eff↑, *toxicity∅, Dose↝, tumCV↓, TumCI↓,
5220- PG,  TMZ,    Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF- κ B Pathway
- in-vitro, GBM, U87MG
TumCMig↓, MMP2↓, MMP9↓, NF-kB↓, ROS↑, selectivity↑,
3339- QC,    Quercetin suppresses ROS production and migration by specifically targeting Rac1 activation in gliomas
- in-vitro, GBM, C6 - in-vitro, GBM, IMR32
BBB↑, tumCV↓, TumCMig↓, Rac1↓, p66Shc↓, ROS↓,
3371- QC,    Quercetin induces MGMT+ glioblastoma cells apoptosis via dual inhibition of Wnt3a/β-Catenin and Akt/NF-κB signaling pathways
- in-vitro, GBM, T98G
TIMP2↑, TumCG↓, TumCMig↓, Apoptosis↑, TumCCA↑, MMP↓, ROS↑, Bax:Bcl2↑, cl‑Casp9↑, cl‑Casp3↑, DNAdam↑, γH2AX↑, MGMT↓, cl‑PARP↑,
3072- RES,    Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway
- in-vitro, GBM, LN229 - in-vitro, GBM, U87MG
tumCV↓, TumCP↓, TumCMig↓, Apoptosis↑, NLRP3↓, JAK2↓, STAT3↓, IL1β↓, IL18↓, IL6↓, TNF-α↓, Inflam↓,
2127- TQ,    Therapeutic Potential of Thymoquinone in Glioblastoma Treatment: Targeting Major Gliomagenesis Signaling Pathways
- Review, GBM, NA
chemoP↑, ChemoSen↑, BioAv↑, PTEN↑, PI3K↓, Akt↓, TumCCA↓, NF-kB↓, p‑Akt↓, p65↓, XIAP↓, Bcl-2↓, COX2↓, VEGF↓, mTOR↓, RAS↓, Raf↓, MEK↓, ERK↓, MMP2↓, MMP9↓, TumCMig↓, TumCI↓, Casp↑, cl‑PARP↑, ROS⇅, ROS↑, MMP↓, eff↑, Telomerase↓, DNAdam↑, Apoptosis↑, STAT3↓, RadioS↑,

Showing Research Papers: 1 to 17 of 17

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 17

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   HO-1↓, 1,   HO-1↑, 1,   NRF2↓, 1,   NRF2↑, 1,   p66Shc↓, 1,   ROS↓, 1,   ROS↑, 4,   ROS⇅, 1,   mt-ROS↑, 1,  

Mitochondria & Bioenergetics ⓘ

MEK↓, 3,   MMP↓, 2,   Raf↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

ACLY↓, 1,   NADPH↓, 1,  

Cell Death ⓘ

Akt↓, 4,   p‑Akt↓, 3,   Apoptosis↑, 8,   Bax:Bcl2↑, 1,   Bcl-2↓, 2,   Casp↑, 1,   Casp3↑, 2,   cl‑Casp3↑, 1,   cl‑Casp9↑, 1,   Ferroptosis↑, 1,   MAPK↓, 2,   Telomerase↓, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 7,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   DNMT1↑, 1,   MGMT↓, 1,   cl‑PARP↑, 2,   γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↓, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State ⓘ

CD133↓, 2,   Diff↑, 1,   ERK↓, 3,   ERK↝, 1,   mTOR↓, 1,   Nestin↓, 1,   NOTCH1↓, 1,   PI3K↓, 3,   p‑PI3K↓, 1,   PTEN↑, 1,   RAS↓, 2,   STAT3↓, 2,   p‑STAT3↓, 1,   TRPM7↓, 2,   TumCG↓, 4,  

Migration ⓘ

p‑Cofilin↑, 2,   F-actin↓, 1,   Ki-67↓, 1,   MMP2↓, 6,   MMP9↓, 3,   N-cadherin?, 1,   NEDD9↓, 1,   Rac1↓, 1,   TIMP2↑, 1,   TumCI↓, 11,   TumCMig↓, 17,   TumCP↓, 4,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   EGFR↓, 1,   EPR↑, 1,   VEGF↓, 1,  

Barriers & Transport ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IL18↓, 1,   IL1β↓, 1,   IL6↓, 1,   Inflam↓, 1,   JAK2↓, 1,   NF-kB↓, 2,   p65↓, 1,   PD-L1↑, 1,   TNF-α↓, 1,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   ChemoSen↑, 2,   Dose↝, 2,   eff↑, 6,   RadioS↑, 1,   selectivity↑, 4,  

Clinical Biomarkers ⓘ

EGFR↓, 1,   IL6↓, 1,   Ki-67↓, 1,   PD-L1↑, 1,  

Functional Outcomes ⓘ

AntiDiabetic↑, 1,   cardioP↑, 1,   chemoP↑, 1,   neuroP↑, 1,   OS↑, 1,   toxicity↓, 1,   TumVol↓, 1,  
Total Targets: 96

Pathway results for Effect on Normal Cells:


Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Functional Outcomes ⓘ

toxicity∅, 2,  
Total Targets: 3

Scientific Paper Hit Count for: TumCMig, Tumor cell migration
2 Carvacrol
2 Quercetin
1 Andrographis
1 Berberine
1 Betulinic acid
1 chitosan
1 Selenium NanoParticles
1 Chrysin
1 Curcumin
1 Hydrogen Gas
1 HydroxyCitric Acid
1 Honokiol
1 Magnetic Field Rotating
1 immunotherapy
1 Magnetic Fields
1 Propyl gallate
1 temozolomide
1 Resveratrol
1 Thymoquinone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:27  Cells:%  prod#:%  Target#:326  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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