Rac1 Cancer Research Results

Rac1, Ras-related C3 botulinum toxin substrate 1: Click to Expand ⟱
Source:
Type:
Rac1 is a small GTPase that plays a crucial role in various cellular processes, including cell growth, migration, and survival.
Rac1 is involved in the regulation of cell migration and invasion, which are critical steps in the metastasis of cancer cells.
Rac1 has been found to be overexpressed in cancer tissues and cell lines, and its expression has been associated with poor prognosis.
Where Low Rac1 expression is found it has been associated with good prognosis and improved overall survival.
GBM, Glioblastoma: Click to Expand ⟱
Glioblastoma is a fast-growing and aggressive brain tumor.
Scientific Papers found: Click to Expand⟱
3339- QC,    Quercetin suppresses ROS production and migration by specifically targeting Rac1 activation in gliomas
- in-vitro, GBM, C6 - in-vitro, GBM, IMR32
BBB↑, tumCV↓, TumCMig↓, Rac1↓, p66Shc↓, ROS↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

p66Shc↓, 1,   ROS↓, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

Migration ⓘ

Rac1↓, 1,   TumCMig↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Rac1, Ras-related C3 botulinum toxin substrate 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:27  Cells:%  prod#:%  Target#:879  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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