antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
GBM, Glioblastoma: Click to Expand ⟱
Glioblastoma is a fast-growing and aggressive brain tumor.
Scientific Papers found: Click to Expand⟱
2731- BetA,    Betulinic Acid for Glioblastoma Treatment: Reality, Challenges and Perspectives
- Review, GBM, NA - Review, Park, NA - Review, AD, NA
BBB↑, *GSH↑, *Catalase↑, *motorD↑, *neuroP↑, *cognitive↑, *ROS↓, *antiOx↑, *Inflam↓, MMP↓, STAT3↓, NF-kB↓, Sp1/3/4↓, TOP1↓, EMT↓, Hif1a↓, VEGF↓, ChemoSen↑, RadioS↑, BioAv↓,
2082- HNK,    Revealing the role of honokiol in human glioma cells by RNA-seq analysis
- in-vitro, GBM, U87MG - in-vitro, GBM, U251
AntiCan↑, TumCP↑, TumAuto↑, Apoptosis↑, *BioAv↑, *neuroP↑, *NF-kB↑, MAPK↑, GPx4↑, Tf↑, BAX↑, Bcl-2↓, antiOx↑, Hif1a↓, Ferroptosis↑,
3485- MF,    Cytoprotective effects of low-frequency pulsed electromagnetic field against oxidative stress in glioblastoma cells
- in-vitro, GBM, U87MG
*antiOx↑, *ROS↓, *cytoP↑,
2259- MFrot,  MF,    Method and apparatus for oncomagnetic treatment
- in-vitro, GBM, NA
MMP↓, Bcl-2↓, BAX↑, Bak↑, Cyt‑c↑, Casp3↑, Casp9↑, DNAdam↑, ROS↑, lactateProd↑, Apoptosis↑, MPT↑, *selectivity↑, eff↑, MMP↓, selectivity↑, TCA?, H2O2↑, eff↑, *antiOx↑, H2O2↑, eff↓, GSH/GSSG↓, *toxicity∅, OS↑,
3302- SIL,    Protective effects of silymarin in glioblastoma cancer cells through redox system regulation
- in-vitro, GBM, U87MG
NRF2↑, HO-1↑, Trx↑, antiOx↑,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   Ferroptosis↑, 1,   GPx4↑, 1,   GSH/GSSG↓, 1,   H2O2↑, 2,   HO-1↑, 1,   NRF2↑, 1,   ROS↑, 1,   Trx↑, 1,  

Metal & Cofactor Biology ⓘ

Tf↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 3,   MPT↑, 1,  

Core Metabolism/Glycolysis ⓘ

lactateProd↑, 1,   TCA?, 1,  

Cell Death ⓘ

Apoptosis↑, 2,   Bak↑, 1,   BAX↑, 2,   Bcl-2↓, 2,   Casp3↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,   Ferroptosis↑, 1,   MAPK↑, 1,  

Kinase & Signal Transduction ⓘ

Sp1/3/4↓, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   STAT3↓, 1,   TOP1↓, 1,  

Migration ⓘ

TumCP↑, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 2,   VEGF↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   ChemoSen↑, 1,   eff↓, 1,   eff↑, 2,   RadioS↑, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   OS↑, 1,  
Total Targets: 42

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 3,   Catalase↑, 1,   GSH↑, 1,   ROS↓, 2,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,   NF-kB↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

cognitive↑, 1,   cytoP↑, 1,   motorD↑, 1,   neuroP↑, 2,   toxicity∅, 1,  
Total Targets: 13

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
2 Magnetic Fields
1 Betulinic acid
1 Honokiol
1 Magnetic Field Rotating
1 Silymarin (Milk Thistle) silibinin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:27  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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