ACSL4 Cancer Research Results

ACSL4, Acyl-CoA Synthetase Long-Chain Family Member 4: Click to Expand ⟱

Source:

Type:

ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4) is a protein that plays a crucial role in the regulation of fatty acid metabolism, particularly in the context of cancer.
ACSL4 has been shown to be highly expressed in various types of cancer.

GBM, Glioblastoma: Click to Expand ⟱

Glioblastoma is a fast-growing and aggressive brain tumor.

Scientific Papers found: Click to Expand⟱

575-

ART/DHA,

Dihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition

in-vitro,

GBM,

U87MG

GPx4↓, xCT∅, ROS↑, Ferroptosis↑, ACSL4∅,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1, GPx4↓, 1, ROS↑, 1, xCT∅, 1,

Core Metabolism/Glycolysis ⓘ

ACSL4∅, 1,

Cell Death ⓘ

Ferroptosis↑, 1,
Total Targets: 6

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: ACSL4, Acyl-CoA Synthetase Long-Chain Family Member 4

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells