Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.


GC, Gastric Adenocarcinoma: Click to Expand ⟱
Stomach/Gastric Cancer

Scientific Papers found: Click to Expand⟱
2667- AL,    Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment
- Review, GC, NA
AntiCan↑, ChemoSen↑, angioG↓, chemoP↑, *GutMicro↑, *antiOx↑, other↝, GSH↓, Thiols↓, *ROS↓, *hepatoP↑, *Inflam↓, *NF-kB↓,
4708- CUR,    Molecular mechanisms underlying curcumin-mediated microRNA regulation in carcinogenesis; Focused on gastrointestinal cancers
- Review, GC, NA
chemoPv↑, AntiCan↑, *antiOx↑, *Inflam↓, miR-21↓, miR-34a↑, miR-200b↑, miR-27a-3p↓,
1607- EA,    Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions
- Review, GC, NA
STAT3↓, TumCP↓, Apoptosis↑, NF-kB↓, EMT↓, RadioS↑, antiOx↑, COX1↓, COX2↓, cMyc↓, Snail↓, Twist↓, MMP2↓, P90RSK↓, CDK8↓, PI3K↓, Akt↓, TumCCA↑, Casp8↑, PCNA↓, TGF-β↓, Shh↓, NOTCH↓, IL6↓, ALAT↓, ALP↓, AST↓, VEGF↓, P21↑, *toxicity∅, *Inflam↓, *cardioP↑, *neuroP↑, *hepatoP↑, ROS↑, *NRF2↓, *GSH↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

antiOx↑, 1,   GSH↓, 1,   ROS↑, 1,   Thiols↓, 1,  

Core Metabolism/Glycolysis

ALAT↓, 1,   cMyc↓, 1,  

Cell Death

Akt↓, 1,   Apoptosis↑, 1,   Casp8↑, 1,  

Transcription & Epigenetics

miR-21↓, 1,   miR-27a-3p↓, 1,   other↝, 1,  

DNA Damage & Repair

PCNA↓, 1,  

Cell Cycle & Senescence

P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

CDK8↓, 1,   EMT↓, 1,   miR-34a↑, 1,   NOTCH↓, 1,   P90RSK↓, 1,   PI3K↓, 1,   Shh↓, 1,   STAT3↓, 1,  

Migration

miR-200b↑, 1,   MMP2↓, 1,   Snail↓, 1,   TGF-β↓, 1,   TumCP↓, 1,   Twist↓, 1,  

Angiogenesis & Vasculature

angioG↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling

COX1↓, 1,   COX2↓, 1,   IL6↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance

ChemoSen↑, 1,   RadioS↑, 1,  

Clinical Biomarkers

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   IL6↓, 1,  

Functional Outcomes

AntiCan↑, 2,   chemoP↑, 1,   chemoPv↑, 1,  
Total Targets: 44

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 2,   GSH↑, 1,   NRF2↓, 1,   ROS↓, 1,  

Immune & Inflammatory Signaling

Inflam↓, 3,   NF-kB↓, 1,  

Clinical Biomarkers

GutMicro↑, 1,  

Functional Outcomes

cardioP↑, 1,   hepatoP↑, 2,   neuroP↑, 1,   toxicity∅, 1,  
Total Targets: 11

Scientific Paper Hit Count for: Inflam, inflammation
1 Allicin (mainly Garlic)
1 Curcumin
1 Ellagic acid
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:28  Cells:%  prod#:%  Target#:953  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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