GADD45A Cancer Research Results

GADD45A, Growth Arrest and DNA Damage-inducible 45 alpha: Click to Expand ⟱
Source:
Type: TSG/protein
GADD45A (Growth Arrest and DNA Damage-inducible 45 alpha) is a protein that plays a crucial role in various cellular processes, including cell cycle regulation, DNA repair, and apoptosis.
GADD45A is a tumor suppressor gene that is often downregulated in various types of cancer, including breast, lung, and colon cancer.
GC, Gastric Adenocarcinoma: Click to Expand ⟱
Stomach/Gastric Cancer
Scientific Papers found: Click to Expand⟱
454- CUR,    Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway
- in-vitro, GC, MGC803
TumCMig↓, TumCP↓, ROS↑, mtDam↑, DNAdam↑, Apoptosis↑, ATR↑, P21↑, p‑P53↑, GADD45A↑, p‑γH2AX↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Mitochondria & Bioenergetics ⓘ

mtDam↑, 1,  

Cell Death ⓘ

Apoptosis↑, 1,  

DNA Damage & Repair ⓘ

ATR↑, 1,   DNAdam↑, 1,   GADD45A↑, 1,   p‑P53↑, 1,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

P21↑, 1,  

Migration ⓘ

TumCMig↓, 1,   TumCP↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: GADD45A, Growth Arrest and DNA Damage-inducible 45 alpha
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:28  Cells:%  prod#:%  Target#:718  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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