AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
Source:
Type: general indicator
Anticancer Effect


GC, Gastric Adenocarcinoma: Click to Expand ⟱
Stomach/Gastric Cancer
Scientific Papers found: Click to Expand⟱
4552- AgNPs,  ART/DHA,    Green synthesis of silver nanoparticles using Artemisia turcomanica leaf extract and the study of anti-cancer effect and apoptosis induction on gastric cancer cell line (AGS)
- in-vitro, GC, AGS
AntiCan↑, Apoptosis↑, eff↑,
5356- AL,    Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects
- Review, GC, NA
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
2667- AL,    Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment
- Review, GC, NA
AntiCan↑, ChemoSen↑, angioG↓, chemoP↑, *GutMicro↑, *antiOx↑, other↝, GSH↓, Thiols↓, *ROS↓, *hepatoP↑, *Inflam↓, *NF-kB↓,
5501- Ba,    Therapeutic effects and mechanisms of action of Baicalein on stomach cancer: a comprehensive systematic literature review
- Review, GC, NA
AntiCan↑, Apoptosis↑, TumCP↓, TumMeta↓, BAX↑, TumAuto↑, ROS↑, NRF2↝, PI3K↓, Akt↓, NF-kB↓, TGF-β↓, SMAD4↓, GPx4↓, MMP↓, *HO-1↑, *GSTs↑, *antiOx↑, *AntiTum↑, *NRF2↑, ChemoSen↑, Akt↓, mTOR↓, FAK↓, Ki-67↓,
4708- CUR,    Molecular mechanisms underlying curcumin-mediated microRNA regulation in carcinogenesis; Focused on gastrointestinal cancers
- Review, GC, NA
chemoPv↑, AntiCan↑, *antiOx↑, *Inflam↓, miR-21↓, miR-34a↑, miR-200b↑, miR-27a-3p↓,
4794- Lyco,    Anticancer Effect of Lycopene in Gastric Carcinogenesis
- Review, GC, NA
*AntiCan↑, *ROS↓, *GSH↑, *GPx↑, *GSTs↑, TumCG↓, Apoptosis↑, ERK↓, Bcl-2↓, BAX↑, Cyt‑c↑, TumCCA↑, *DNAdam↓,
4793- Lyco,    Lycopene treatment inhibits activation of Jak1/Stat3 and Wnt/β-catenin signaling and attenuates hyperproliferation in gastric epithelial cells
- in-vitro, GC, AGS
antiOx↑, AntiCan↑, ROS↓, JAK1↓, STAT3↓, Wnt↓, β-catenin/ZEB1↓, cMyc↓, cycE/CCNE↓, TumCP↓, Risk↓,
4533- MAG,    Magnolol, a natural compound, induces apoptosis of SGC-7901 human gastric adenocarcinoma cells via the mitochondrial and PI3K/Akt signaling pathways
- in-vitro, GC, SGC-7901
AntiCan↑, DNAdam↑, Apoptosis↑, TumCCA↑, Bax:Bcl2↑, MMP↓, Casp3↑, PI3K↓, Akt↓,

Showing Research Papers: 1 to 8 of 8

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   GPx4↓, 1,   GSH↓, 1,   NRF2↝, 1,   ROS↓, 1,   ROS↑, 2,   Thiols↓, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↑, 1,   MMP↓, 3,  

Core Metabolism/Glycolysis ⓘ

cMyc↓, 1,   H2S↑, 1,  

Cell Death ⓘ

Akt↓, 4,   Apoptosis↑, 6,   BAX↑, 3,   Bax:Bcl2↑, 1,   Bcl-2↓, 2,   Casp↑, 1,   Casp3↑, 1,   Casp8↑, 1,   Cyt‑c↑, 2,   Fas↑, 1,   MAPK↓, 1,  

Transcription & Epigenetics ⓘ

miR-21↓, 1,   miR-27a-3p↓, 1,   other↝, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↑, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   p‑P53↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence ⓘ

CDK4↓, 1,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 2,   P21↑, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,   miR-34a↑, 1,   mTOR↓, 1,   PI3K↓, 3,   STAT3↓, 1,   TumCG↓, 1,   Wnt↓, 1,  

Migration ⓘ

Ca+2↑, 1,   FAK↓, 1,   Ki-67↓, 1,   miR-200b↑, 1,   SMAD4↓, 1,   TGF-β↓, 2,   TumCP↓, 3,   TumMeta↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   HIF-1↓, 1,  

Immune & Inflammatory Signaling ⓘ

JAK1↓, 1,   NF-kB↓, 2,   NF-kB↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   ChemoSen↑, 3,   eff↑, 1,   RadioS↑, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

Ki-67↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 7,   chemoP↑, 1,   chemoPv↑, 1,   Risk↓, 1,  
Total Targets: 68

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 3,   GPx↑, 1,   GSH↑, 1,   GSTs↑, 2,   HO-1↑, 1,   NRF2↑, 2,   ROS↓, 2,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 2,   NF-kB↓, 1,  

Clinical Biomarkers ⓘ

GutMicro↑, 2,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiTum↑, 1,   chemoP↑, 1,   hepatoP↑, 1,  
Total Targets: 15

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
2 Allicin (mainly Garlic)
2 Lycopene
1 Silver-NanoParticles
1 Artemisinin
1 Baicalein
1 Curcumin
1 Magnolol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:28  Cells:%  prod#:%  Target#:813  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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