ACSL4 Cancer Research Results
ACSL4, Acyl-CoA Synthetase Long-Chain Family Member 4: Click to Expand ⟱
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ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4) is a protein that plays a crucial role in the regulation of fatty acid metabolism, particularly in the context of cancer.
ACSL4 has been shown to be highly expressed in various types of cancer.
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GC, Gastric Adenocarcinoma: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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vitro+vivo, |
GC, |
HGC27 |
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vitro+vivo, |
GC, |
MKN45 |
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TumCP↓, TumCMig↓, TumCI↓, TumCG↓, *toxicity↓, eff↑, Ferroptosis↑, ACSL4↑, GPx4↓, ChemoSen↑, chemoP↑, AntiTum↑, Sepsis↓,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
Ferroptosis↑, 1, GPx4↓, 1,
Core Metabolism/Glycolysis ⓘ
ACSL4↑, 1,
Cell Death ⓘ
Ferroptosis↑, 1,
Proliferation, Differentiation & Cell State ⓘ
TumCG↓, 1,
Migration ⓘ
TumCI↓, 1, TumCMig↓, 1, TumCP↓, 1,
Drug Metabolism & Resistance ⓘ
ChemoSen↑, 1, eff↑, 1,
Functional Outcomes ⓘ
AntiTum↑, 1, chemoP↑, 1,
Infection & Microbiome ⓘ
Sepsis↓, 1,
Total Targets: 13
Pathway results for Effect on Normal Cells:
Functional Outcomes ⓘ
toxicity↓, 1,
Total Targets: 1
Scientific Paper Hit Count for: ACSL4, Acyl-CoA Synthetase Long-Chain Family Member 4
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:28 Cells:% prod#:% Target#:867 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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