CDK1 Cancer Research Results

CDK1, Cyclin-dependent kinase 1: Click to Expand ⟱

Source:

Type:

CDK1, (Cyclin-dependent kinase 1) same as p34 (cdc2) kinase activity
Mitotic Gatekeeper, Essential Cell-Cycle Engine, and Therapeutic Vulnerability
Cell cycle control to gene expression regulation and apoptosis, CDK1 is intimately involved in many cellular events that are vital for cell survival.
CDK1 is a significant biomarker in various cancers, with its overexpression often correlating with aggressive tumor characteristics and poor prognosis. Targeting CDK1 may offer therapeutic potential, especially in cancers where its expression is linked to unfavorable outcomes.

Colon, Colon Cancer: Click to Expand ⟱

Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.

Scientific Papers found: Click to Expand⟱

1353-

And,

Andrographolide Induces Apoptosis and Cell Cycle Arrest through Inhibition of Aberrant Hedgehog Signaling Pathway in Colon Cancer Cells

in-vitro,

Colon,

HCT116

ChemoSen↑, TumCCA↑, CDK1↓, CycB/CCNB1↓, HH↓, Smo↓, Gli1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Cycle & Senescence ⓘ

CDK1↓, 1, CycB/CCNB1↓, 1, TumCCA↑, 1,

Proliferation, Differentiation & Cell State ⓘ

Gli1↓, 1, HH↓, 1, Smo↓, 1,

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,
Total Targets: 7

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: CDK1, Cyclin-dependent kinase 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells