CK2 Cancer Research Results

CK2, Casein Kinase 2: Click to Expand ⟱
Source:
Type:
CK2, or Casein Kinase 2, is a serine/threonine kinase that plays a significant role in various cellular processes, including cell growth, proliferation, and survival. Research has shown that CK2 is often overexpressed in various types of cancer, and its activity is associated with tumor progression and resistance to apoptosis (programmed cell death).

-casein kinase 2 (CK2) is a positive regulator in the self-renewal of cervical cancer stem-like cells
Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
Scientific Papers found: Click to Expand⟱
1655- FA,    Ferulic acid inhibiting colon cancer cells at different Duke’s stages
- in-vitro, Colon, SW480 - in-vitro, Colon, Caco-2 - in-vitro, Colon, HCT116
TumCP↓, TumCMig↓, TumCCA↑, Apoptosis↑, ATM↑, Chk2↑, ATR↑, CHK1↑, CK2↓, cycA1/CCNA1↑, CDK4↓, CDK6↓, cycD1/CCND1↓, cycE/CCNE↓, P53↑, P21↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,   Chk2↑, 1,   CK2↓, 1,  

DNA Damage & Repair ⓘ

ATM↑, 1,   ATR↑, 1,   CHK1↑, 1,   P53↑, 1,  

Cell Cycle & Senescence ⓘ

CDK4↓, 1,   cycA1/CCNA1↑, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Migration ⓘ

TumCMig↓, 1,   TumCP↓, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CK2, Casein Kinase 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:31  Cells:%  prod#:%  Target#:524  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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