BMI1 Cancer Research Results

BMI1, B cell-specific Moloney murine leukemia virus integration site 1: Click to Expand ⟱
Source:
Type:
BMI1 (B cell-specific Moloney murine leukemia virus integration site 1) is a protein that plays a crucial role in the regulation of cell growth, differentiation, and survival. It is a key component of the Polycomb repressive complex 1 (PRC1), which is involved in the silencing of genes through histone modification.
Overexpression of BMI1 has been observed in many types of cancer, and it is often associated with poor prognosis and reduced survival rates.
Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
Scientific Papers found: Click to Expand⟱
4928- PEITC,    Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers
- vitro+vivo, Colon, SW-620
Risk↓, HDAC↓, TumW↓, TumCG↓, AP-1↓, cAMP↓, NF-kB↓, BMI1↓, SUZ12↓, EZH2↓, selectivity↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

cAMP↓, 1,  

Transcription & Epigenetics ⓘ

EZH2↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

BMI1↓, 1,   HDAC↓, 1,   SUZ12↓, 1,   TumCG↓, 1,  

Migration ⓘ

AP-1↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  

Drug Metabolism & Resistance ⓘ

selectivity↑, 1,  

Clinical Biomarkers ⓘ

EZH2↓, 1,   SUZ12↓, 1,  

Functional Outcomes ⓘ

Risk↓, 1,   TumW↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: BMI1, B cell-specific Moloney murine leukemia virus integration site 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:31  Cells:%  prod#:%  Target#:837  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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