MMP9 Cancer Research Results
MMP9, MMP9: Click to Expand ⟱
| Source: HalifaxProj(suppress) |
| Type: |
Matrix metalloproteinase-9 (MMP-9) is an enzyme that plays a significant role in the degradation of extracellular matrix components.
MMP-9 facilitates the breakdown of the extracellular matrix, which can enable cancer cells to invade surrounding tissues and spread to distant sites (metastasis).
Elevated levels of MMP-9 have been associated with poor prognosis in several cancers, including breast, lung, and colorectal cancers.
MMP2 and MMP9: two enzymes are critical to tumor invasion.
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Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
Colon, |
SW480 |
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in-vitro, |
Colon, |
CT26 |
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TumCP↓, TumCMig↑, TumCI↑, EMT↑, MMP2↓, MMP9↑, STAT3↑, TumMeta↑, ROS↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
Proliferation, Differentiation & Cell State ⓘ
EMT↑, 1, STAT3↑, 1,
Migration ⓘ
MMP2↓, 1, MMP9↑, 1, TumCI↑, 1, TumCMig↑, 1, TumCP↓, 1, TumMeta↑, 1,
Total Targets: 9
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: MMP9, MMP9
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:31 Cells:% prod#:% Target#:203 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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