cycA1/CCNA1 Cancer Research Results
cycA1/CCNA1, cyclin A1: Click to Expand ⟱
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Cyclin A1 is a protein that plays a crucial role in the regulation of the cell cycle, which is the process by which cells grow and divide. It is overexpressed in various types of cancer, including breast, ovarian, and colorectal cancer, and its overexpression has been linked to poor prognosis and reduced survival rates.
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Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
Colon, |
SW480 |
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in-vitro, |
Colon, |
Caco-2 |
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in-vitro, |
Colon, |
HCT116 |
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TumCP↓, TumCMig↓, TumCCA↑, Apoptosis↑, ATM↑, Chk2↑, ATR↑, CHK1↑, CK2↓, cycA1/CCNA1↑, CDK4↓, CDK6↓, cycD1/CCND1↓, cycE/CCNE↓, P53↑, P21↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Apoptosis↑, 1, Chk2↑, 1, CK2↓, 1,
DNA Damage & Repair ⓘ
ATM↑, 1, ATR↑, 1, CHK1↑, 1, P53↑, 1,
Cell Cycle & Senescence ⓘ
CDK4↓, 1, cycA1/CCNA1↑, 1, cycD1/CCND1↓, 1, cycE/CCNE↓, 1, P21↑, 1, TumCCA↑, 1,
Migration ⓘ
TumCMig↓, 1, TumCP↓, 1,
Hormonal & Nuclear Receptors ⓘ
CDK6↓, 1,
Total Targets: 16
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: cycA1/CCNA1, cyclin A1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:31 Cells:% prod#:% Target#:653 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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