COX1 Cancer Research Results
COX1, COX-1: Click to Expand ⟱
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COX‑1 is traditionally considered a constitutively expressed enzyme involved in “housekeeping” functions, while COX‑2 is more frequently studied in relation to cancer.
• The prognostic impact of COX‑1 may vary based on cancer subtype, stage, and interplay with other inflammatory mediators (e.g., COX‑2).
• Many studies assess combined cyclooxygenase profiles (COX‑1/COX‑2) rather than COX‑1 alone.
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Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
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Scientific Papers found: Click to Expand⟱
ROS↓, Inflam↓, TumCP↓, Apoptosis↑, *Dose↝, *BioAv↓, *BioAv↑, GSH↑, GSTs↑, PGE2↓, COX1↑, IL8↓, COX2↓, iNOS↓, NF-kB↓, chemoP↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSH↑, 1, GSTs↑, 1, ROS↓, 1,
Cell Death ⓘ
Apoptosis↑, 1, iNOS↓, 1,
Migration ⓘ
TumCP↓, 1,
Immune & Inflammatory Signaling ⓘ
COX1↑, 1, COX2↓, 1, IL8↓, 1, Inflam↓, 1, NF-kB↓, 1, PGE2↓, 1,
Functional Outcomes ⓘ
chemoP↑, 1,
Total Targets: 13
Pathway results for Effect on Normal Cells:
Drug Metabolism & Resistance ⓘ
BioAv↓, 1, BioAv↑, 1, Dose↝, 1,
Total Targets: 3
Scientific Paper Hit Count for: COX1, COX-1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:31 Cells:% prod#:% Target#:998 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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