Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
Source:
Type:
Drug dosage vs efficacy, and actual dosage number of research papers.
Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
Scientific Papers found: Click to Expand⟱
304- ALA,    alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation
- in-vitro, Colon, HT-29
mt-ROS↑, Apoptosis↑, Casp3↑, DNAdam↑, Bcl-xL↓, Dose↝,
6083- CHOC,    Preventive Effects of Cocoa and Cocoa Antioxidants in Colon Cancer
- Review, Colon, NA
ROS↓, Inflam↓, TumCP↓, Apoptosis↑, *Dose↝, *BioAv↓, *BioAv↑, GSH↑, GSTs↑, PGE2↓, COX1↑, IL8↓, COX2/PTGS2↓, iNOS↓, NF-kB↓, chemoP↑,
6428- FEO,  Eug,    Triggering of apoptosis and cell cycle arrest by fennel and clove oils in Caco-2 cells: the role of combination
- in-vitro, Colon, Caco-2
TumCCA↑, Apoptosis↑, Dose↝, TumCCA↑, Ki-67↓,
7014- Fuc,  5-FU,    Low-Molecular-Weight Fucoidan as Complementary Therapy of Fluoropyrimidine-Based Chemotherapy in Colorectal Cancer
- in-vitro, CRC, HCT116 - in-vitro, Colon, Caco-2
tumCV↓, ChemoSen↑, TumCCA↑, cl‑PARP↑, KRAS↓, p‑ERK↓, PI3K↓, p‑Akt↓, TumCMig↓, MMP2↓, Dose↝,
8256- LCA,    Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice
- in-vivo, Colon, CT26
TumVol?, TumCP↓, *RenoP↑, *creat↓, BUN↓, hepatoP↑, *ALAT↓, *AST↓, *NO↓, *lipid-P↓, *GSH↑, chemoP↑, Dose↝,
7921- VT,    Vitexin's Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches
- in-vitro, Colon, Caco-2
Dose↝, tumCV↓, SOD↓, Catalase↓, MDA↑, P53↑, BAX↓, TSC2↑, SESN2↑, PUMA↑, AMPK↑, PI3K↑, Akt↑, mTOR↓,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 1,   GSH↑, 1,   GSTs↑, 1,   MDA↑, 1,   ROS↓, 1,   mt-ROS↑, 1,   SOD↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   BUN↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   p‑Akt↓, 1,   Apoptosis↑, 3,   BAX↓, 1,   Bcl-xL↓, 1,   Casp3↑, 1,   iNOS↓, 1,   PUMA↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

SESN2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   P53↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 3,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑ERK↓, 1,   mTOR↓, 1,   PI3K↓, 1,   PI3K↑, 1,  

Migration(tgid=13) ⓘ

Ki-67↓, 1,   KRAS↓, 1,   MMP2↓, 1,   TumCMig↓, 1,   TumCP↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↑, 1,   COX2/PTGS2↓, 1,   IL8↓, 1,   Inflam↓, 1,   NF-kB↓, 1,   PGE2↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   Dose↝, 5,  

Clinical Biomarkers(tgid=22) ⓘ

Ki-67↓, 1,   KRAS↓, 1,  

Functional Outcomes(tgid=23) ⓘ

chemoP↑, 2,   hepatoP↑, 1,   TumVol?, 1,  
Total Targets: 46

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH↑, 1,   lipid-P↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   creat↓, 1,  

Functional Outcomes(tgid=23) ⓘ

RenoP↑, 1,  
Total Targets: 11

Scientific Paper Hit Count for: Dose, Dosage
1 Alpha-Lipoic-Acid
1 Chocolate
1 Fennel Oil/Foeniculum vulgare
1 Eugenol
1 Fucoidan
1 5-fluorouracil
1 Licochalcone A
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:31  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:4
  wNotes=0  sortOrder:rid,rpid

 

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