ITGB1 Cancer Research Results

ITGB1, Integrin beta-1: Click to Expand ⟱

Source:

Type:

ITGB1, also known as Integrin beta-1 or β1-integrin, is a protein that plays a crucial role in cell adhesion, migration, and signaling. It is a transmembrane receptor that interacts with various extracellular matrix proteins, such as collagen, laminin, and fibronectin.
ITGB1 is overexpressed in: breast, lung, colon, prostate, CRC, ovarian, pancreatic, gastric, esophageal, melanoma, GBM

Bladder, Bladder Cancer: Click to Expand ⟱

Bladder Cancer

Scientific Papers found: Click to Expand⟱

295-

ALA,

α-Lipoic acid suppresses migration and invasion via downregulation of cell surface β1-integrin expression in bladder cancer cells

in-vitro,

Bladder,

T24/HTB-9

ITGB1↓, TumCMig↓, ERK↓, Akt↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

Akt↓, 1,

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,

Migration ⓘ

ITGB1↓, 1, TumCMig↓, 1,
Total Targets: 4

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: ITGB1, Integrin beta-1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells