AQPs Cancer Research Results

AQPs, Aquaporins: Click to Expand ⟱

Source:

Type:

Aquaporins are membrane proteins that form channels to facilitate water transport across cell membranes. They are essential for maintaining water homeostasis in various tissues, and research over the past decade has revealed their involvement in several aspects of cancer biology.
• Aquaporins can influence cell proliferation. Some studies have shown that overexpression of specific aquaporin isoforms (like AQP1, AQP3, and AQP5) is associated with increased cell proliferation in different cancer types.
-increased expression of AQP1 or AQP3 has been correlated with poor prognosis in some cancers.

Arthritis, Arthritis: Click to Expand ⟱

Arthritis

Scientific Papers found: Click to Expand⟱

5486-

BM,

Bacopaside I, acting as an aquaporin 1 inhibitor, ameliorates rheumatoid arthritis via suppressing aquaporin 1-mediated autophagy

in-vivo,

Arthritis,

rat adjuvant-induced arthritis (AIA)

*AQPs↓, TumCP↓, Apoptosis↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

Apoptosis↑, 1,

Migration ⓘ

TumCP↓, 1,
Total Targets: 2

Pathway results for Effect on Normal Cells:

Barriers & Transport ⓘ

AQPs↓, 1,
Total Targets: 1

Scientific Paper Hit Count for: AQPs, Aquaporins

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells