Cancer Research Results

, aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (): In Alzheimer’s disease, peptides tend to misfold and aggregate into oligomers and fibrils.


Arthritis, Arthritis: Click to Expand ⟱
Arthritis


Scientific Papers found: Click to Expand⟱
3343- QC,    Quercetin, a Flavonoid with Great Pharmacological Capacity
- Review, Var, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *angioG↓, *Inflam↓, *BioAv↓, *Half-Life↑, *GSH↑, *SOD↑, *Catalase↑, *Nrf1↑, *BP↓, *cardioP↑, *IL10↓, *TNF-α↓, *↓, *GSK‐3β↓, *tau↓, *neuroP↑, *Pain↓, *COX2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL17↓, *MCP1↓, PKCδ↓, ERK↓, BAX↓, cMyc↓, KRAS↓, ROS↓, selectivity↑, tumCV↓, Apoptosis↑, TumCCA↑, eff↑, P-gp↓, eff↑, eff↑, eff↑, eff↑, CycB/CCNB1↓, CDK1↓, CDK4↓, CDK2↓, TOP2↓, Cyt‑c↑, cl‑PARP↑, MMP↓, HSP70/HSPA5↓, HSP90↓, MDM2↓, RAS↓, eff↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

ROS↓, 1,  

Mitochondria & Bioenergetics

MMP↓, 1,  

Core Metabolism/Glycolysis

cMyc↓, 1,  

Cell Death

Apoptosis↑, 1,   BAX↓, 1,   Cyt‑c↑, 1,   MDM2↓, 1,  

Transcription & Epigenetics

tumCV↓, 1,  

Protein Folding & ER Stress

HSP70/HSPA5↓, 1,   HSP90↓, 1,  

DNA Damage & Repair

cl‑PARP↑, 1,  

Cell Cycle & Senescence

CDK1↓, 1,   CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

ERK↓, 1,   RAS↓, 1,   TOP2↓, 1,  

Migration

KRAS↓, 1,   PKCδ↓, 1,  

Barriers & Transport

P-gp↓, 1,  

Drug Metabolism & Resistance

eff↑, 6,   selectivity↑, 1,  

Clinical Biomarkers

KRAS↓, 1,  
Total Targets: 25

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   Catalase↑, 1,   GSH↑, 1,   HO-1↑, 1,   Nrf1↑, 1,   NRF2↑, 1,   ROS↓, 1,   SOD↑, 1,  

Proliferation, Differentiation & Cell State

GSK‐3β↓, 1,  

Angiogenesis & Vasculature

angioG↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   IL10↓, 1,   IL17↓, 1,   IL1β↓, 1,   Inflam↓, 1,   MCP1↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission

tau↓, 1,  

Protein Aggregation

↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   Half-Life↑, 1,  

Clinical Biomarkers

BP↓, 1,  

Functional Outcomes

cardioP↑, 1,   neuroP↑, 1,   Pain↓, 1,  
Total Targets: 25

Scientific Paper Hit Count for: , aggregation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:35  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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