MMP13 Cancer Research Results

MMP13, MMP13: Click to Expand ⟱
Source:
Type:
MMP-13, or matrix metalloproteinase-13, is an enzyme that plays a significant role in the degradation of extracellular matrix components. It is involved in various physiological processes, including tissue remodeling, wound healing, and bone development.
MMP-13 is often overexpressed in various types of cancers, including breast, colorectal, and lung cancers.
Arthritis, Arthritis: Click to Expand ⟱
Arthritis
Scientific Papers found: Click to Expand⟱
3589- PI,    Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models
- in-vivo, Arthritis, NA
*IL6↓, *MMP13↓, *PGE2↓, *AP-1↓, *Inflam↓, *5LO↓, *COX1↓, *COX2↓, *ERK↓, *BioEnh↑,
3931- PTS,    Pterostilbene Protects against Osteoarthritis through NLRP3 Inflammasome Inactivation and Improves Gut Microbiota as Evidenced by In Vivo and In Vitro Studies
- in-vivo, Arthritis, NA
*Inflam↓, *NLRP3↓, *GutMicro↑, *lipid-P↓, *ROS↓, *Cartilage↑, *IL6↓, *MMP13↓, *Dose↝,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

lipid-P↓, 1,   ROS↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,  

Migration ⓘ

5LO↓, 1,   AP-1↓, 1,   Cartilage↑, 1,   MMP13↓, 2,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 1,   COX2↓, 1,   IL6↓, 2,   Inflam↓, 2,   PGE2↓, 1,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioEnh↑, 1,   Dose↝, 1,  

Clinical Biomarkers ⓘ

GutMicro↑, 1,   IL6↓, 2,  
Total Targets: 17

Scientific Paper Hit Count for: MMP13, MMP13
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:35  Cells:%  prod#:%  Target#:199  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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