hepatoP Cancer Research Results

hepatoP, L,hepatoprotective: Click to Expand ⟱
Source:
Type:
Hepatoprotective is the ability of a chemical substance to prevent damage to the liver.

Grapefruit:
-hepatoprotective potential has emerged from the study of naringenin and naringin.
Blueberries/cranberries:
-proanthocyanidins
Grape:
Nopal (Cactus pear) and tuna (Cactus pear fruit) “Opuntia ficus-indica”:
Chamomile (Matricaria chamomilla or Chamomilla recutita):
Silymarin (Silybum marianum):
Blue green algae spirulina :
Propolis (bee glue):

POLYSACCHARIDES
β-glucans


Arthritis, Arthritis: Click to Expand ⟱
Arthritis


Scientific Papers found: Click to Expand⟱
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
3929- PTS,    New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects
- Review, Var, NA - Review, Arthritis, NA
*NRF2↑, *BioAv↑, *ROS↓, *Inflam↓, *HO-1↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *hepatoP↑, *neuroP↑, *iNOS↓, *COX2↓, TumMeta↓, SOD2↓, ROS↑, TumCI↓, TumCG↓, HDAC1↓, PTEN↑, BP↓, *GutMicro↑,
3933- RT,    The Pharmacological Potential of Rutin
- Review, AD, NA - Review, Stroke, NA - Review, Arthritis, NA
*antiOx↑, *neuroP↑, *cardioP↑, *Inflam↓, *TNF-α↓, *IL1β↓, *IL8↓, *COX2↓, *iNOS↓, *NF-kB↓, *cognitive↑, *Cartilage↑, *AntiAg↑, *ROS↓, *lipid-P↓, *hepatoP↑, *ALAT↓, *AST↓, *RenoP↑,
3294- SIL,    Silymarin: a review on paving the way towards promising pharmacological agent
- Review, Nor, NA - Review, Arthritis, NA
*hepatoP↑, *Inflam↓, *chemoP↑, *glucose↓, *antiOx↑, *ROS↓, *ACC↓, *FASN↓, *radioP↑, *NF-kB↓, *TGF-β↓, *AST↓, *α-SMA↝, *eff↑, *neuroP↑, eff↑, ROS↓,
2415- SK,    Shikonin induces programmed death of fibroblast synovial cells in rheumatoid arthritis by inhibiting energy pathways
- in-vivo, Arthritis, NA
Apoptosis?, TumAuto↑, ROS↑, ATP↓, Glycolysis↓, PI3K↓, Akt↓, mTOR↓, *Apoptosis↓, *Inflam↓, *TNF-α↓, *IL6↓, *IL8↓, *IL10↓, *IL17↓, *hepatoP↑, *RenoP↑, PKM2↓, GLUT1↓, HK2↓,
5904- TV,    Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Obesity, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

H2O2↑, 1,   lipid-P↑, 1,   ROS↓, 1,   ROS↑, 2,   i-ROS↑, 1,   SOD2↓, 1,  

Metal & Cofactor Biology

IronCh↑, 1,  

Mitochondria & Bioenergetics

AIF↑, 1,   ATP↓, 1,   MMP↓, 1,  

Core Metabolism/Glycolysis

Glycolysis↓, 1,   HK2↓, 1,   PKM2↓, 1,  

Cell Death

Akt↓, 1,   APAF1↑, 1,   Apoptosis?, 1,   Apoptosis↑, 1,   BAX↑, 2,   Bcl-2↓, 1,   Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,  

Autophagy & Lysosomes

TumAuto↑, 1,  

DNA Damage & Repair

DNAdam↑, 2,   cl‑PARP↑, 1,  

Cell Cycle & Senescence

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

ERK↓, 1,   HDAC1↓, 1,   mTOR↓, 1,   PI3K↓, 1,   PTEN↑, 1,   TumCG↓, 1,  

Migration

Ca+2↑, 2,   MMP2↓, 1,   MMP9↓, 1,   PKCδ↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,   TumMeta↓, 1,  

Angiogenesis & Vasculature

angioG↓, 1,  

Barriers & Transport

GLUT1↓, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,  

Drug Metabolism & Resistance

ChemoSen↑, 2,   eff↑, 1,  

Clinical Biomarkers

BP↓, 1,  

Functional Outcomes

AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 1,   cognitive↑, 1,   hepatoP↑, 1,   radioP↑, 1,   RenoP↑, 1,  
Total Targets: 54

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 3,   Catalase↑, 2,   GPx↑, 3,   GSH↑, 2,   GSTs↑, 1,   H2O2↓, 1,   HDL↑, 1,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 1,   MPO↓, 1,   NADH↓, 1,   NRF2↑, 1,   RNS↓, 1,   ROS?, 1,   ROS↓, 5,   SOD↑, 4,  

Mitochondria & Bioenergetics

MMP↑, 1,  

Core Metabolism/Glycolysis

ACC↓, 1,   ALAT↓, 1,   FASN↓, 1,   glucose↓, 1,   LDL↓, 1,  

Cell Death

Apoptosis↓, 1,   iNOS↓, 2,  

Transcription & Epigenetics

other↓, 1,   other↑, 1,  

Proliferation, Differentiation & Cell State

STAT3↓, 1,  

Migration

AntiAg↑, 2,   Cartilage↑, 1,   MMP2↓, 1,   MMP9↓, 1,   TGF-β↓, 1,   α-SMA↝, 1,  

Angiogenesis & Vasculature

NO↓, 1,  

Barriers & Transport

BBB↑, 1,   GastroP↑, 1,  

Immune & Inflammatory Signaling

COX1↓, 1,   COX2↓, 4,   IL10↓, 1,   IL10↑, 1,   IL17↓, 1,   IL1β↓, 2,   IL6↓, 2,   IL8↓, 2,   Imm↑, 1,   Inflam↓, 5,   NF-kB↓, 3,   PGE2↓, 1,   TNF-α↓, 3,  

Synaptic & Neurotransmission

AChE↓, 1,   BChE↓, 1,   BDNF↑, 1,  

Protein Aggregation

β-Amyloid↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 3,   BioAv↝, 3,   Dose↝, 1,   eff↑, 3,   Half-Life↝, 1,  

Clinical Biomarkers

ALAT↓, 1,   AST↓, 2,   BP↓, 1,   GutMicro↑, 2,   IL6↓, 2,   NOS2↓, 1,  

Functional Outcomes

AntiDiabetic↑, 1,   cardioP↑, 2,   chemoP↑, 1,   cognitive↑, 2,   hepatoP↑, 5,   neuroP↑, 4,   Obesity↓, 1,   radioP↑, 1,   RenoP↑, 2,  

Infection & Microbiome

Bacteria↓, 1,  
Total Targets: 75

Scientific Paper Hit Count for: hepatoP, L,hepatoprotective
1 Baicalein
1 Baicalin
1 Pterostilbene
1 Rutin
1 Silymarin (Milk Thistle) silibinin
1 Shikonin
1 Thymol-Thymus vulgaris
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:35  Cells:%  prod#:%  Target#:1179  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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