eff Cancer Research Results

eff, efficacy: Click to Expand ⟱
Source:
Type:
Power to enhance an anti cancer effect
Arthritis, Arthritis: Click to Expand ⟱
Arthritis
Scientific Papers found: Click to Expand⟱
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2/PTGS2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
4620- Bor,  BTZ,    Boron Compounds in the Breast Cancer Cells Chemoprevention and Chemotherapy
- Review, Var, NA - Review, Arthritis, NA - Review, Pca, NA
Risk↓, *memory↑, *Dose↑, Risk↓, other↝, *testos↑, other↝, Risk↓, TumCP↓, Apoptosis↑, eff↑,
4625- Bor,    Boron and Inflammation
- Review, Arthritis, NA - Review, ostP, NA
*Risk↓, *eff↑, *SOD↑, *NF-kB↓, *Risk↓, *CRP↓, *TNF-α↓, *Wound Healing↑,
3583- CUR,    Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers
- Review, Arthritis, NA
*TNF-α↓, *IL1β↓, *NF-kB↓, *PGE2↓, *COX2/PTGS2↓, *MMPs↓, *eff↑,
6820- EMD,    The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb—A Summary Update
- Review, Nor, NA - Review, Arthritis, NA - Review, AD, NA
*diuretic↑, *Bacteria↓, *Inflam↓, AntiCan↑, TumCP↓, TumCI↓, angioG↓, *toxicity↓, IFN-γ↑, IL12↑, ROS↑, TNF-α↓, TNF-α↓, TGF-β↓, MAPK↓, PKCδ↓, NF-kB↓, HER2/EBBR2↓, VEGF↓, DNAdam↑, Necroptosis↑, Glycolysis↓, GLUT1↓, PI3K↓, Akt↓, Casp9↑, Casp3↑, BAX↑, Bcl-2↓, eff↑, MMP2↓, MMP9↓, eff↑, ChemoSen↑, P-gp/ABCB1↓, SREBP2↓, eff↑, *other↝, *COX2/PTGS2↓, *Hif1a↓, *HDAC↓, *tau↓, *PKCδ↑, *ROS↓, *Inflam↓, AntiAg?,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, eff↑, eff↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
6941- MF,  Ex,    The effects of pulsed electromagnetic field therapy on muscle strength and pain in patients with end-stage knee osteoarthritis: a randomized controlled trial
- Trial, Arthritis, NA
*Strength↑, *Pain↓, *eff↑, *Dose↝,
3568- MF,    The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis
- Review, Arthritis, NA
*eff↑, *Pain↓, *motorD↑,
3847- MSM,    Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement
- Review, Arthritis, NA
*Inflam↓, *Pain↓, *ROS↓, *antiOx↑, *Dose↝, *Half-Life↝, *NF-kB↓, *IL1↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *NLRP3↓, *NRF2↑, *STAT↓, *Cartilage↑, *eff↑, *eff↑, *GSH↑, *uricA↓, tumCV↓, TumCCA↑, necrosis↑, Apoptosis↑, VEGF↓, HSP90↓, IGF-1?,
3343- QC,    Quercetin, a Flavonoid with Great Pharmacological Capacity
- Review, Var, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *angioG↓, *Inflam↓, *BioAv↓, *Half-Life↑, *GSH↑, *SOD↑, *Catalase↑, *Nrf1↑, *BP↓, *cardioP↑, *IL10↓, *TNF-α↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroP↑, *Pain↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL17↓, *MCP1/CCL2↓, PKCδ↓, ERK↓, BAX↓, cMyc↓, KRAS↓, ROS↓, selectivity↑, tumCV↓, Apoptosis↑, TumCCA↑, eff↑, P-gp/ABCB1↓, eff↑, eff↑, eff↑, eff↑, CycB/CCNB1↓, CDK1↓, CDK4↓, CDK2↓, TOP2↓, Cyt‑c↑, cl‑PARP↑, MMP↓, HSP70/HSPA5↓, HSP90↓, MDM2↓, RAS↓, eff↑,
3294- SIL,    Silymarin: a review on paving the way towards promising pharmacological agent
- Review, Nor, NA - Review, Arthritis, NA
*hepatoP↑, *Inflam↓, *chemoP↑, *glucose↓, *antiOx↑, *ROS↓, *ACC↓, *FASN↓, *radioP↑, *NF-kB↓, *TGF-β↓, *AST↓, *α-SMA↝, *eff↑, *neuroP↑, eff↑, ROS↓,
5904- TV,    Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Obesity, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2/PTGS2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,

Showing Research Papers: 1 to 12 of 12

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 12

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

H2O2↑, 1,   lipid-P↑, 1,   ROS↓, 2,   ROS↑, 1,   i-ROS↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   MMP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,   Glycolysis↓, 1,   SREBP2↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   APAF1↑, 1,   Apoptosis↑, 5,   BAX↓, 1,   BAX↑, 3,   Bcl-2↓, 2,   Casp3↑, 4,   Casp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 2,   MAPK↓, 1,   MDM2↓, 1,   Necroptosis↑, 1,   necrosis↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 2,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP70/HSPA5↓, 1,   HSP90↓, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 3,   cl‑PARP↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   P21↑, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 2,   FOXO3↑, 1,   IGF-1?, 1,   PI3K↓, 1,   RAS↓, 1,   TOP2↓, 1,  

Migration(tgid=13) ⓘ

AntiAg?, 1,   Ca+2↑, 2,   KRAS↓, 1,   MMP2↓, 2,   MMP9↓, 2,   PKCδ↓, 3,   TGF-β↓, 1,   TumCI↓, 3,   TumCMig↓, 2,   TumCP↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 3,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   P-gp/ABCB1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IFN-γ↑, 1,   IL12↑, 1,   Inflam↓, 1,   NF-kB↓, 2,   TNF-α↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 4,   eff↑, 13,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

HER2/EBBR2↓, 1,   KRAS↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 1,   cognitive↑, 1,   hepatoP↑, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 3,  
Total Targets: 79

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 1,   diuretic↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 5,   Catalase↑, 3,   GPx↑, 3,   GSH↑, 6,   GSTs↑, 1,   H2O2↓, 1,   HDL↑, 1,   HO-1↑, 1,   MDA↓, 3,   MPO↓, 1,   NADH↓, 1,   Nrf1↑, 1,   NRF2↑, 2,   RNS↓, 1,   ROS?, 1,   ROS↓, 7,   SOD↑, 5,   TAC↑, 1,   uricA↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↓, 1,   FASN↓, 1,   glucose↓, 2,   LDL↓, 1,  

Cell Death(tgid=5) ⓘ

iNOS↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↑, 1,   other↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↓, 1,   HDAC↓, 1,   STAT↓, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   Cartilage↑, 1,   MMP2↓, 1,   MMP9↓, 1,   MMPs↓, 1,   PKCδ↑, 1,   TGF-β↓, 1,   α-SMA↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   Hif1a↓, 1,   NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GastroP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 6,   CRP↓, 1,   IL1↓, 1,   IL10↓, 2,   IL10↑, 1,   IL17↓, 1,   IL1β↓, 3,   IL6↓, 3,   Imm↑, 1,   Inflam↓, 7,   Inflam↑, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 5,   PGE2↓, 2,   TNF-α↓, 6,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BChE↓, 1,   BDNF↑, 1,   tau↓, 2,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   NLRP3↓, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 3,   BioAv⇅, 1,   BioAv↝, 4,   Dose↑, 1,   Dose↝, 3,   eff↑, 9,   Half-Life↑, 1,   Half-Life↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

AST↓, 1,   BP↓, 2,   CRP↓, 1,   GutMicro↑, 2,   IL6↓, 3,   NOS2↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 3,   cardioP↑, 3,   chemoP↑, 1,   cognitive↑, 1,   hepatoP↑, 2,   memory↑, 1,   motorD↑, 1,   neuroP↑, 4,   Obesity↓, 1,   Pain↓, 4,   radioP↑, 1,   Risk↓, 2,   Strength↑, 1,   toxicity↓, 1,   toxicity↝, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 2,  
Total Targets: 104

Scientific Paper Hit Count for: eff, efficacy
2 Boron
2 Magnetic Fields
1 Baicalein
1 Baicalin
1 Bortezomib
1 Curcumin
1 Emodin
1 Eugenol
1 Exercise
1 Methylsulfonylmethane
1 Quercetin
1 Silymarin (Milk Thistle) silibinin
1 Thymol-Thymus vulgaris
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:35  Cells:%  prod#:%  Target#:961  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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