Sepsis Cancer Research Results

Sepsis, Sepsis: Click to Expand ⟱
Source:
Type:
Sepsis is a life-threatening medical condition that occurs when the body’s response to an infection causes widespread inflammation. This uncontrolled inflammatory response can lead to tissue damage, organ failure, and, in severe cases, death.

-Treatment options PKM2, Glycolysis and HIF1α inhibitors.

-Chemotherapy, radiation therapy, and immunosuppressive drugs can further weaken the immune system, making patients more susceptible to infections that can lead to sepsis.

-AgNPs have demonstrated antimicrobial effects against a wide range of pathogens including bacteria, fungi, and viruses. Since infections are the primary trigger for sepsis, their ability to reduce microbial loads has been of significant interest.


Stroke, Cerebral Ischemic Stroke: Click to Expand ⟱
Ischemic stroke is also called brain ischemia and cerebral ischemia. Ischemia is the medical term for "lack of blood supply."


Scientific Papers found: Click to Expand⟱
2760- BetA,    A Review on Preparation of Betulinic Acid and Its Biological Activities
- Review, Var, NA - Review, Stroke, NA
AntiTum↑, Cyt‑c↑, Smad1↑, Sepsis↓, NF-kB↓, ICAM-1↓, MCP1↓, MMP9↓, COX2↓, PGE2↓, ERK↓, p‑Akt↓, *ROS↓, *LDH↓, *hepatoP↑, *SOD↑, *Catalase↑, *GSH↑, *AST↓, *ALAT↓, *RenoP↑, *ROS↓, *α-SMA↓,
3869- Carno,    Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *IronCh↑, *AntiAge↑, *antiOx↑, *Inflam↓, *neuroP↑, *lipid-P↓, *toxicity↓, *NOX4↓, *SOD↑, *HNE↓, *IL6↓, *TNF-α↓, *IL1β↓, *Sepsis↓, *eff↑, *GABA↝, *Aβ↓, Glycolysis↓, AntiTum↑, p‑Akt↓, TumCCA↑, angioG↓, VEGFR2↓, NF-kB↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis

Glycolysis↓, 1,  

Cell Death

p‑Akt↓, 2,   Cyt‑c↑, 1,  

Cell Cycle & Senescence

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

ERK↓, 1,  

Migration

MMP9↓, 1,   Smad1↑, 1,  

Angiogenesis & Vasculature

angioG↓, 1,   VEGFR2↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   ICAM-1↓, 1,   MCP1↓, 1,   NF-kB↓, 2,   PGE2↓, 1,  

Functional Outcomes

AntiTum↑, 2,  

Infection & Microbiome

Sepsis↓, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   Catalase↑, 1,   GSH↑, 1,   HNE↓, 1,   lipid-P↓, 1,   NOX4↓, 1,   ROS↓, 3,   SOD↑, 2,  

Metal & Cofactor Biology

IronCh↑, 1,  

Core Metabolism/Glycolysis

ALAT↓, 1,   LDH↓, 1,  

Migration

α-SMA↓, 1,  

Immune & Inflammatory Signaling

IL1β↓, 1,   IL6↓, 1,   Inflam↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission

GABA↝, 1,  

Protein Aggregation

Aβ↓, 1,  

Drug Metabolism & Resistance

eff↑, 1,  

Clinical Biomarkers

ALAT↓, 1,   AST↓, 1,   IL6↓, 1,   LDH↓, 1,  

Functional Outcomes

AntiAge↑, 1,   hepatoP↑, 1,   neuroP↑, 1,   RenoP↑, 1,   toxicity↓, 1,  

Infection & Microbiome

Sepsis↓, 1,  
Total Targets: 29

Scientific Paper Hit Count for: Sepsis, Sepsis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:36  Cells:%  prod#:%  Target#:1264  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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