mtDam Cancer Research Results

mtDam, mitochondrial damage: Click to Expand ⟱
Source:
Type:
Mitochondrial damage can lead to a shift from oxidative phosphorylation to glycolysis, a process known as the Warburg effect. This shift can provide cancer cells with a selective advantage, allowing them to grow and proliferate more rapidly.
Mitochondrial Damage can also lead to cell death of cancer cells.


Stroke, Cerebral Ischemic Stroke: Click to Expand ⟱
Ischemic stroke is also called brain ischemia and cerebral ischemia. Ischemia is the medical term for "lack of blood supply."


Scientific Papers found: Click to Expand⟱
5430- AG,    Review of the pharmacological effects of astragaloside IV and its autophagic mechanism in association with inflammation
- Review, Stroke, NA
*cardioP↑, *MitoP↑, *ROS↓, *mtDam↓, *neuroP↓, TumAuto↓, *AntiDiabetic↑,
5552- BBM,    Effects of berbamine against myocardial ischemia/reperfusion injury: Activation of the 5' adenosine monophosphate‐activated protein kinase/nuclear factor erythroid 2‐related factor pathway and changes in the mitochondrial state
- in-vivo, Stroke, NA
*eff↑, *ROS↓, *mtDam↓, *AMPK↑, *NRF2↑, *NADPH↑, *HO-1↑, *cardioP↑,
3261- Lyco,    Lycopene and Vascular Health
- Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiAg↑, *cardioP↑, *SOD↑, *Catalase↑, *ROS↓, *mtDam↓, *cardioP↑, *NF-kB↓, *NO↓, *COX2↓, *LDL↓, *eff↑, *ER Stress↓, *BioAv↑, *eff↑, *MMPs↓, *COX2↓, *RAGE↓,
2933- NAD,    Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns
- Review, Nor, NA - NA, AD, NA - NA, Diabetic, NA - NA, Stroke, NA - NA, LiverDam, NA - NA, Park, NA
*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Autophagy & Lysosomes

TumAuto↓, 1,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   Catalase↑, 1,   HO-1↑, 1,   NRF2↑, 1,   ROS↓, 4,   SOD↑, 1,  

Mitochondria & Bioenergetics

mtDam↓, 4,  

Core Metabolism/Glycolysis

AMPK↑, 1,   LDL↓, 1,   NADPH↑, 1,   SIRT1↑, 1,  

Protein Folding & ER Stress

ER Stress↓, 1,  

Autophagy & Lysosomes

MitoP↑, 1,  

DNA Damage & Repair

DNAdam↓, 1,  

Migration

AntiAg↑, 1,   MMPs↓, 1,   RAGE↓, 1,  

Angiogenesis & Vasculature

NO↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 2,   Inflam↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 3,   BioAv↝, 1,   Dose↝, 1,   eff↑, 6,  

Clinical Biomarkers

BG↓, 1,   creat↓, 1,   RAGE↓, 1,  

Functional Outcomes

AntiDiabetic↑, 1,   cardioP↑, 5,   cognitive↑, 1,   hepatoP↑, 1,   neuroP↓, 1,   OS↑, 1,  
Total Targets: 34

Scientific Paper Hit Count for: mtDam, mitochondrial damage
1 Astragalus
1 Berbamine
1 Lycopene
1 nicotinamide adenine dinucleotide
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:36  Cells:%  prod#:%  Target#:614  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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