AntiAg Cancer Research Results

AntiAg, Antiplatelet aggregation: Click to Expand ⟱
Source:
Type:
Antiplatelet aggregation refers to the process by which platelets clump together to form a blood clot.
The plethora of evidence indicates that among multiple hemostasis components, platelets play major roles in cancer progression by providing surface and granular contents for several interactions as well as behaving like immune cells.On the other hand, there are suggestions that antiplatelet treatment may promote solid tumor development in a phenomenon described as “cancers follow bleeding.” The controversies around antiplatelet agents justify insight into the subject to establish what, if any, role platelet-directed therapy has in the continuum of anticancer management.
The interplay between antiplatelet aggregation and cancer is an area of active research, with potential implications for therapeutic strategies. Antiplatelet agents, such as aspirin, are being investigated for their role in cancer prevention and treatment, particularly in reducing metastasis and improving patient outcomes.


Stroke, Cerebral Ischemic Stroke: Click to Expand ⟱
Ischemic stroke is also called brain ischemia and cerebral ischemia. Ischemia is the medical term for "lack of blood supply."


Scientific Papers found: Click to Expand⟱
4577- AgNPs,    Characterization of Antiplatelet Properties of Silver Nanoparticles
- vitro+vivo, Stroke, NA
*AntiAg↑, *Bacteria↓, *Dose↝, *Dose↝, *Dose↝, *toxicity↝,
5888- CAR,    Therapeutic application of carvacrol: A comprehensive review
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Park, NA
*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2↓, *MDA↓,
6084- CHOC,    Cocoa Polyphenols and Their Potential Benefits for Human Health
- Review, Nor, NA - Review, Stroke, NA - Review, IBD, NA
*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2↓, *Obesity↓, *cognitive↑,
3261- Lyco,    Lycopene and Vascular Health
- Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiAg↑, *cardioP↑, *SOD↑, *Catalase↑, *ROS↓, *mtDam↓, *cardioP↑, *NF-kB↓, *NO↓, *COX2↓, *LDL↓, *eff↑, *ER Stress↓, *BioAv↑, *eff↑, *MMPs↓, *COX2↓, *RAGE↓,
2567- RES,    Neuroprotective Effects of Resveratrol in Ischemic Brain Injury
- Review, Stroke, NA
*eff↑, *neuroP↑, *antiOx↑, *Inflam↓, *cardioP↑, *AntiAg↑,
2566- RES,    A comprehensive review on the neuroprotective potential of resveratrol in ischemic stroke
- Review, Stroke, NA
*neuroP↑, *NRF2↑, *SIRT1↑, *PGC-1α↑, *FOXO↑, *HO-1↑, *NQO1↑, *ROS↓, *BP↓, *BioAv↓, *Half-Life↝, *AMPK↑, *GSK‐3β↓, *eff↑, *AntiAg↑, *BBB↓, *Inflam↓, *MPO↓, *TLR4↓, *NF-kB↓, *p65↓, *MMP9↓, *TNF-α↓, *IL1β↓, *PPARγ↑, *MMP↑, *ATP↑, *Cyt‑c∅, *mt-lipid-P↓, *H2O2↓, *HSP70/HSPA5↝, *Mets↝, *eff↑, *eff↑, *motorD↑, *MDA↓, *NADH:NAD↑, eff↑, eff↑,
4284- RES,    Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
- in-vitro, AD, HEK293 - NA, Stroke, NA - in-vivo, AD, NA
*p‑tau↓, *PP2A↑, *neuroP↑, *antiOx↑, COX2↓, *AntiAg↑, *SIRT1↑, *AMPK↑, *Acetyl-CoA↓, *FAO↑, *ADAM10↑, *BACE↓, *Aβ↓, *memory↑, *Inflam↓, *ROS↓,
3933- RT,    The Pharmacological Potential of Rutin
- Review, AD, NA - Review, Stroke, NA - Review, Arthritis, NA
*antiOx↑, *neuroP↑, *cardioP↑, *Inflam↓, *TNF-α↓, *IL1β↓, *IL8↓, *COX2↓, *iNOS↓, *NF-kB↓, *cognitive↑, *Cartilage↑, *AntiAg↑, *ROS↓, *lipid-P↓, *hepatoP↑, *ALAT↓, *AST↓, *RenoP↑,
5904- TV,    Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Obesity, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,

Showing Research Papers: 1 to 9 of 9

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 9

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

CYP1A1↓, 1,   H2O2↑, 1,   lipid-P↑, 1,   ROS↑, 1,   i-ROS↑, 1,  

Metal & Cofactor Biology

IronCh↑, 1,  

Mitochondria & Bioenergetics

AIF↑, 1,   MMP↓, 2,  

Core Metabolism/Glycolysis

ALAT↓, 1,  

Cell Death

APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 1,   BAX↑, 2,   Bcl-2↓, 1,   Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,  

DNA Damage & Repair

DNAdam↑, 2,   cl‑PARP↑, 1,  

Cell Cycle & Senescence

CDK4↓, 1,   cycD1/CCND1↓, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State

ERK↓, 2,   NOTCH↓, 1,   PI3K↓, 1,  

Migration

Ca+2↑, 2,   MMP2↓, 2,   MMP9↓, 2,   PKCδ↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature

angioG↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 2,   IL6↓, 1,  

Drug Metabolism & Resistance

ChemoSen↑, 1,   eff↑, 2,  

Clinical Biomarkers

ALAT↓, 1,   IL6↓, 1,  

Functional Outcomes

AntiTum↑, 1,   chemoP↑, 2,   hepatoP↑, 1,   radioP↑, 1,   RenoP↑, 1,  
Total Targets: 44

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 7,   Catalase↑, 3,   GPx↑, 3,   GSH↑, 1,   GSTs↑, 1,   H2O2↓, 2,   HDL↑, 1,   HO-1↑, 1,   lipid-P↓, 2,   mt-lipid-P↓, 1,   MDA↓, 3,   Mets↝, 1,   MPO↓, 1,   NADH↓, 1,   NQO1↑, 1,   NRF2↑, 1,   RNS↓, 1,   ROS↓, 7,   SOD↑, 4,  

Mitochondria & Bioenergetics

ATP↑, 1,   MMP↑, 1,   mtDam↓, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis

Acetyl-CoA↓, 1,   ALAT↓, 1,   AMPK↑, 2,   FAO↑, 1,   LDH↓, 1,   LDL↓, 2,   NADH:NAD↑, 1,   PPARγ↑, 1,   SIRT1↑, 2,  

Cell Death

Cyt‑c∅, 1,   iNOS↓, 1,   necrosis↓, 1,  

Transcription & Epigenetics

other↓, 2,   other↑, 1,  

Protein Folding & ER Stress

ER Stress↓, 1,   HSP70/HSPA5↝, 1,  

Proliferation, Differentiation & Cell State

FOXO↑, 1,   GSK‐3β↓, 1,   TRPM7↓, 1,  

Migration

5LO↓, 1,   AntiAg↑, 9,   Cartilage↑, 1,   MMP9↓, 1,   MMPs↓, 1,   RAGE↓, 1,  

Angiogenesis & Vasculature

NO↓, 2,  

Barriers & Transport

BBB↓, 1,   GastroP↑, 1,  

Immune & Inflammatory Signaling

COX1↓, 1,   COX2↓, 5,   IL1β↓, 2,   IL8↓, 1,   Imm↑, 3,   Inflam↓, 7,   NF-kB↓, 5,   p65↓, 1,   TLR4↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission

AChE↓, 1,   ADAM10↑, 1,   BChE↓, 1,   p‑tau↓, 1,  

Protein Aggregation

Aβ↓, 1,   BACE↓, 1,   PP2A↑, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   BioAv↑, 3,   BioAv⇅, 1,   BioAv↝, 1,   Dose↝, 3,   eff↑, 7,   Half-Life↝, 2,  

Clinical Biomarkers

ALAT↓, 1,   AST↓, 2,   BP↓, 3,   LDH↓, 1,   NOS2↓, 1,   RAGE↓, 1,  

Functional Outcomes

AntiCan↑, 1,   AntiDiabetic↑, 2,   cardioP↑, 7,   chemoPv↑, 1,   cognitive↑, 3,   hepatoP↑, 2,   memory↑, 1,   motorD↑, 2,   neuroP↑, 5,   Obesity↓, 3,   Pain↓, 1,   RenoP↑, 1,   Risk↓, 1,   toxicity↝, 1,  

Infection & Microbiome

Bacteria↓, 3,  
Total Targets: 96

Scientific Paper Hit Count for: AntiAg, Antiplatelet aggregation
3 Resveratrol
1 Silver-NanoParticles
1 Carvacrol
1 Chocolate
1 Lycopene
1 Rutin
1 Thymol-Thymus vulgaris
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:36  Cells:%  prod#:%  Target#:10  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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