Apoptosis Cancer Research Results
Apoptosis, Apoptosis: Click to Expand ⟱
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| Type: type of cell death |
Situation in which a cell actively pursues a course toward death upon receiving certain stimuli.
Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die.
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Stroke, Cerebral Ischemic Stroke: Click to Expand ⟱
Ischemic stroke is also called brain ischemia and cerebral ischemia. Ischemia is the medical term for "lack of blood supply."
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Scientific Papers found: Click to Expand⟱
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Review, |
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NA |
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Stroke, |
NA |
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Park, |
NA |
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*antiOx↑, *Inflam↓, *hepatoP↑, *neuroP↑, *BioAv↓, *cardioP↑, *lipidLev↓, *RenoP↑, *TNF-α↓, *IL2↓, *PI3K↓, *Akt↓, *ROS↓, *cognitive↑, eff↑, cycD1/CCND1↓, hTERT/TERT↓, VEGF↓, p‑STAT3↓, TumMeta↓, TumCP↓, eff↑, eff↑, IL1β↓, IL6↓, NF-kB↓, ROS↑, MMP↓, Cyt‑c↑, Apoptosis↑, ER Stress↑, Ca+2↑, TET1↑, Let-7↑, Twist↓, EMT↓, TumCCA↑, Casp3↑, Casp9↑, BAX↑, HK2↓, GlucoseCon↓, lactateProd↓, Glycolysis↓, SHP1↑, N-cadherin↓, E-cadherin↑, UPR↑, PERK↑, ATF4↑, eIF2α↑, RadioS↑, NOTCH1↑, NRF2↓, BioAv↑, eff↑,
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Var, |
NA |
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IBD, |
NA |
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Stroke, |
NA |
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*Half-Life↝, *BioAv↓, *BioAv↑, *BioAv↑, *Inflam↓, *TNF-α↓, *other↑, *MPO↓, *COX2↓, *NF-kB↑, *STAT3↑, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *Catalase↑, *GPx↑, *Bcl-2↑, *BAX↓, cardioP↑, AntiCan↑, NF-kB↓, ROS↑, PKM2↓, TumCCA↑, Necroptosis↑, Apoptosis↑, DNAdam↑, MMP↓, Cyt‑c↑, LDH↝,
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Var, |
NA |
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Stroke, |
NA |
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*BioAv↓, *BioAv↑, *Inflam↓, *antiOx↑, *ROS↓, *GSH↑, *GSTs↑, *MPO↓, *NF-kB↓, *COX2↓, *IL1β↓, *TNF-α↓, *IFN-γ↓, *IL6↓, *cardioP↑, *lipid-P↓, *TAC↑, *RenoP↑, Apoptosis↑, TumCCA↑, TumCP↓, TumCMig↓, angioG↓, TNF-α↓, NF-kB↓, ROS↑, EMT↓, *Aβ↓, *p‑tau↓, *BACE↓, *TLR2↓, *TLR4↓, *MyD88↓, *IRF3↓, *eff↑, eff↑, DNAdam↑, *iNOS↓,
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Review, |
Var, |
NA |
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Stroke, |
NA |
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Diabetic, |
NA |
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Obesity, |
NA |
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AD, |
NA |
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Arthritis, |
NA |
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*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,
Showing Research Papers: 1 to 4 of 4
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
H2O2↑, 1, lipid-P↑, 1, NRF2↓, 1, ROS↑, 3, i-ROS↑, 1,
Metal & Cofactor Biology ⓘ
IronCh↑, 1,
Mitochondria & Bioenergetics ⓘ
AIF↑, 1, MMP↓, 3,
Core Metabolism/Glycolysis ⓘ
GlucoseCon↓, 1, Glycolysis↓, 1, HK2↓, 1, lactateProd↓, 1, LDH↝, 1, PKM2↓, 1,
Cell Death ⓘ
APAF1↑, 1, Apoptosis↑, 4, BAX↑, 3, Bcl-2↓, 1, Casp3↑, 2, Casp8↑, 1, Casp9↑, 2, Cyt‑c↑, 3, hTERT/TERT↓, 1, Necroptosis↑, 1,
Protein Folding & ER Stress ⓘ
eIF2α↑, 1, ER Stress↑, 1, PERK↑, 1, UPR↑, 1,
DNA Damage & Repair ⓘ
DNAdam↑, 4, cl‑PARP↑, 1,
Cell Cycle & Senescence ⓘ
cycD1/CCND1↓, 1, TumCCA↑, 4,
Proliferation, Differentiation & Cell State ⓘ
EMT↓, 2, ERK↓, 1, Let-7↑, 1, NOTCH1↑, 1, SHP1↑, 1, p‑STAT3↓, 1,
Migration ⓘ
Ca+2↑, 3, E-cadherin↑, 1, MMP2↓, 1, MMP9↓, 1, N-cadherin↓, 1, PKCδ↓, 1, TET1↑, 1, TumCMig↓, 2, TumCP↓, 3, TumMeta↓, 1, Twist↓, 1,
Angiogenesis & Vasculature ⓘ
angioG↓, 2, ATF4↑, 1, VEGF↓, 1,
Immune & Inflammatory Signaling ⓘ
IL1β↓, 1, IL6↓, 1, NF-kB↓, 3, TNF-α↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↑, 1, ChemoSen↑, 1, eff↑, 5, RadioS↑, 1,
Clinical Biomarkers ⓘ
hTERT/TERT↓, 1, IL6↓, 1, LDH↝, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, AntiTum↑, 1, cardioP↑, 1, chemoP↑, 1, hepatoP↑, 1, radioP↑, 1, RenoP↑, 1,
Total Targets: 70
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 4, Catalase↑, 2, GPx↑, 3, GSH↑, 2, GSTs↑, 2, H2O2↓, 1, HDL↑, 1, lipid-P↓, 1, MDA↓, 1, MPO↓, 2, NADH↓, 1, RNS↓, 1, ROS↓, 4, SOD↑, 3, TAC↑, 1,
Core Metabolism/Glycolysis ⓘ
LDL↓, 1, lipidLev↓, 1,
Cell Death ⓘ
Akt↓, 1, BAX↓, 1, Bcl-2↑, 1, iNOS↓, 1,
Transcription & Epigenetics ⓘ
other↓, 1, other↑, 2,
Proliferation, Differentiation & Cell State ⓘ
PI3K↓, 1, STAT3↑, 1,
Migration ⓘ
AntiAg↑, 1,
Angiogenesis & Vasculature ⓘ
NO↓, 1,
Barriers & Transport ⓘ
GastroP↑, 1,
Immune & Inflammatory Signaling ⓘ
COX1↓, 1, COX2↓, 3, IFN-γ↓, 1, IL1β↓, 1, IL2↓, 1, IL6↓, 1, Imm↑, 1, Inflam↓, 4, MyD88↓, 1, NF-kB↓, 1, NF-kB↑, 1, TLR2↓, 1, TLR4↓, 1, TNF-α↓, 3,
Synaptic & Neurotransmission ⓘ
AChE↓, 1, BChE↓, 1, p‑tau↓, 1,
Protein Aggregation ⓘ
Aβ↓, 1, BACE↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↓, 3, BioAv↑, 5, BioAv↝, 1, eff↑, 2, Half-Life↝, 2,
Clinical Biomarkers ⓘ
BP↓, 1, IL6↓, 1, NOS2↓, 1,
Functional Outcomes ⓘ
AntiDiabetic↑, 1, cardioP↑, 3, cognitive↑, 2, hepatoP↑, 1, neuroP↑, 2, Obesity↓, 1, RenoP↑, 2,
Infection & Microbiome ⓘ
Bacteria↓, 1, IRF3↓, 1,
Total Targets: 64
Scientific Paper Hit Count for: Apoptosis, Apoptosis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:36 Cells:% prod#:% Target#:14 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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