angioG Cancer Research Results

angioG, angiogenesis: Click to Expand ⟱
Source:
Type:
Process through which new blood vessels.
Angiogenesis, the process of new blood vessel formation from pre-existing vessels, plays a crucial role in cancer progression and metastasis. Tumors require a blood supply to grow beyond a certain size and to spread to other parts of the body.
Vascular Endothelial Growth Factor (VEGF): VEGF is one of the most important pro-angiogenic factors. It stimulates endothelial cell proliferation and migration, leading to the formation of new blood vessels. Many tumors overexpress VEGF, which correlates with poor prognosis.
Hypoxia-Inducible Factor (HIF): In response to low oxygen levels (hypoxia), tumors can activate HIF, which in turn promotes the expression of VEGF and other angiogenic factors. This mechanism allows tumors to adapt to their microenvironment and sustain growth.


Wounds, Wounds: Click to Expand ⟱
Wounds: Injury to the body, such as the skin.


Scientific Papers found: Click to Expand⟱
3516- Bor,    Boron in wound healing: a comprehensive investigation of its diverse mechanisms
- Review, Wounds, NA
*Inflam↓, *antiOx↑, *ROS↓, *angioG↑, *COL1↑, *α-SMA↑, *TGF-β↑, *BMD↑, *hepatoP↑, *TNF-α↑, *HSP70/HSPA5↑, *SOD↑, *Catalase↑, *GSH↑, *MDA↓, *TOS↓, *IL6↓, *JAK2↓, *STAT3↓, *AMPK↑, *lipid-P↓, *VEGF↑, *Half-Life↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   Catalase↑, 1,   GSH↑, 1,   lipid-P↓, 1,   MDA↓, 1,   ROS↓, 1,   SOD↑, 1,   TOS↓, 1,  

Core Metabolism/Glycolysis

AMPK↑, 1,  

Protein Folding & ER Stress

HSP70/HSPA5↑, 1,  

Proliferation, Differentiation & Cell State

STAT3↓, 1,  

Migration

COL1↑, 1,   TGF-β↑, 1,   α-SMA↑, 1,  

Angiogenesis & Vasculature

angioG↑, 1,   VEGF↑, 1,  

Immune & Inflammatory Signaling

IL6↓, 1,   Inflam↓, 1,   JAK2↓, 1,   TNF-α↑, 1,  

Drug Metabolism & Resistance

Half-Life↝, 1,  

Clinical Biomarkers

BMD↑, 1,   IL6↓, 1,  

Functional Outcomes

hepatoP↑, 1,  
Total Targets: 24

Scientific Paper Hit Count for: angioG, angiogenesis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:37  Cells:%  prod#:%  Target#:447  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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