lipidLev Cancer Research Results

lipidLev, Lipid Levels: Click to Expand ⟱
Source:
Type:
Lipid levels refer to the concentration and distribution of various lipids—including fatty acids, cholesterol, phospholipids, and triglycerides—in cells and tissues. Lipids are essential components of cellular membranes, serve as energy storage molecules, and act as signaling molecules that regulate cellular processes such as growth, apoptosis, and inflammation.

Under normal physiological conditions, lipid levels are tightly regulated by dietary intake, de novo synthesis, uptake, storage, and breakdown. Enzymes (e.g., fatty acid synthase, acetyl-CoA carboxylase) and transcription factors (e.g., SREBP1) coordinate these processes to maintain cellular homeostasis.

Many tumors upregulate de novo lipogenesis to generate lipids internally, even in the presence of exogenous lipids. As a result, cancer cells often have elevated levels of fatty acids and other lipid intermediates. These adjustments not only support rapid growth but also contribute to resistance to stress and apoptosis.


BC, Breast Cancer: Click to Expand ⟱
Breast Cancer

Scientific Papers found: Click to Expand⟱
1191- SM,    Salvia miltiorrhiza extract inhibits TPA‑induced MMP‑9 expression and invasion through the MAPK/AP‑1 signaling pathw
- in-vitro, BC, MCF-7
Inflam↓, MMP9↓, TumCI↓, AP-1↓, lipidLev↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis

lipidLev↓, 1,  

Migration

AP-1↓, 1,   MMP9↓, 1,   TumCI↓, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: lipidLev, Lipid Levels
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:1039  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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