SOX4 Cancer Research Results

SOX4, SRY‐box transcription factor 4: Click to Expand ⟱
Source:
Type:
SOX4 belongs to the SOX (SRY-related HMG-box) family of transcription factors and plays a critical role in embryonic development, differentiation, and cell survival.
• In cancer, SOX4 has been implicated in processes such as epithelial-to-mesenchymal transition (EMT), invasion, metastasis, and resistance to apoptosis.

In many cancers—including breast, colorectal, lung, ovarian, and pancreatic cancers—high SOX4 expression is generally associated with a more aggressive tumor phenotype and poorer clinical outcomes.
BC, Breast Cancer: Click to Expand ⟱
Breast Cancer
Scientific Papers found: Click to Expand⟱
4406- AgNPs,    Silver nanoparticles achieve cytotoxicity against breast cancer by regulating long-chain noncoding RNA XLOC_006390-mediated pathway
- in-vitro, BC, MCF-7 - in-vitro, BC, T47D - in-vitro, BC, MDA-MB-231
TumCD↑, other↓, P53↑, TumCCA↑, Apoptosis↑, ChemoSen↑, tumCV↓, γH2AX↑, SOX4↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,   TumCD↑, 1,  

Transcription & Epigenetics ⓘ

other↓, 1,   tumCV↓, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Migration ⓘ

SOX4↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,  
Total Targets: 9

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SOX4, SRY‐box transcription factor 4
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:1060  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page