ChemoSen Cancer Research Results
ChemoSen, chemo-sensitization: Click to Expand ⟱
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| Type: |
The effectiveness of chemotherapy by increasing cancer cell sensitivity to the drugs used to treat them, which is known as “chemo-sensitization”.
Chemo-Sensitizers:
-Curcumin
-Resveratrol
-EGCG
-Quercetin
-Genistein
-Berberine
-Piperine: alkaloid from black pepper
-Ginsenosides: active components of ginseng
-Silymarin
-Allicin
-Lycopene
-Ellagic acid
-caffeic acid phenethyl ester
-flavopiridol
-oleandrin
-ursolic acid
-butein
-betulinic acid
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BC, Breast Cancer: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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in-vitro, |
BC, |
MCF-7 |
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in-vitro, |
BC, |
MDA-MB-231 |
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eff↓, ROS↑, TumCP↑, NRF2↑, ChemoSen↓,
ChemoSen↓, RadioS↑, Inflam↓, AntiCan↑, Dose∅, mtDam↑, Apoptosis?, OCR↓, ATP↓, ROS↑, ROS↑, LDH↓, TP53↓, Casp3↓, BAX↓, P21↓, ROS↑, eNOS↑, iNOS↑, eff↑, hTERT/TERT↓, cycD1/CCND1↓, eff↑, eff↑, eff↑, eff↑, STAT3↓, TIMP1↓, IL4↓, IL10↓, OS↑, Dose∅, ER Stress↑, ROS↑, NF-kB↓, p65↓, MMP↓, TumAuto↑, LC3II↑, p62↓, TLR4↓, mtDam↑, LDH↓, ROS↑, Glycolysis↓, HK2↓, PFK↓, PKM2↓, LDH↓, IL10↓, HDAC8↓, eff↑, eff↑, P21↑,
Showing Research Papers: 1 to 2 of 2
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
NRF2↑, 1, ROS↑, 6,
Mitochondria & Bioenergetics ⓘ
ATP↓, 1, MMP↓, 1, mtDam↑, 2, OCR↓, 1,
Core Metabolism/Glycolysis ⓘ
Glycolysis↓, 1, HK2↓, 1, LDH↓, 3, PFK↓, 1, PKM2↓, 1,
Cell Death ⓘ
Apoptosis?, 1, BAX↓, 1, Casp3↓, 1, hTERT/TERT↓, 1, iNOS↑, 1,
Protein Folding & ER Stress ⓘ
ER Stress↑, 1,
Autophagy & Lysosomes ⓘ
LC3II↑, 1, p62↓, 1, TumAuto↑, 1,
DNA Damage & Repair ⓘ
TP53↓, 1,
Cell Cycle & Senescence ⓘ
cycD1/CCND1↓, 1, P21↓, 1, P21↑, 1,
Proliferation, Differentiation & Cell State ⓘ
HDAC8↓, 1, STAT3↓, 1,
Migration ⓘ
TIMP1↓, 1, TumCP↑, 1,
Angiogenesis & Vasculature ⓘ
eNOS↑, 1,
Immune & Inflammatory Signaling ⓘ
IL10↓, 2, IL4↓, 1, Inflam↓, 1, NF-kB↓, 1, p65↓, 1, TLR4↓, 1,
Drug Metabolism & Resistance ⓘ
ChemoSen↓, 2, Dose∅, 2, eff↓, 1, eff↑, 7, RadioS↑, 1,
Clinical Biomarkers ⓘ
hTERT/TERT↓, 1, LDH↓, 3, TP53↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, OS↑, 1,
Total Targets: 45
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: ChemoSen, chemo-sensitization
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:4 Cells:% prod#:% Target#:1106 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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