FOXM1 Cancer Research Results
FOXM1, FOXM1 transcription factor: Click to Expand ⟱
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FOXM1 transcription factor is a regulator of a broad range of biological processes.
Master Driver of Proliferation, Genomic Instability, and Therapy Resistance
Elevated and deregulated FOXM1 expression is found in a wide spectrum of cancers. FOXM1 also plays a central role in cancer initiation, progression and anti-cancer drug resistance. FOXM1 is repeatedly overexpressed in a variety of human cancers.
High FOXM1 expression is associated with aggressive tumor characteristics and poor overall survival. FOXM1 is generally considered a marker of poor prognosis across various cancer types.
FOXM1 is used as a clinical biomarker for Epigentic instability
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BC, Breast Cancer: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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in-vitro, |
BC, |
MCF-7 |
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in-vitro, |
BC, |
T47D |
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in-vivo, |
NA, |
NA |
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ERα/ESR1↓, TumCG↓, ROS↑, FOXM1↓, eff↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
Proliferation, Differentiation & Cell State ⓘ
FOXM1↓, 1, TumCG↓, 1,
Hormonal & Nuclear Receptors ⓘ
ERα/ESR1↓, 1,
Drug Metabolism & Resistance ⓘ
eff↑, 1,
Clinical Biomarkers ⓘ
ERα/ESR1↓, 1, FOXM1↓, 1,
Total Targets: 7
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: FOXM1, FOXM1 transcription factor
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:4 Cells:% prod#:% Target#:351 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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