MDA Cancer Research Results

MDA, Serum malondialdehyde: Click to Expand ⟱
Source:
Type:
MDA : malondialdehyde. The level of oxidative stress can be measured by assessing the MDA levels.
Since MDA is highly cytotoxic and carcinogenic agent it is frequently used as a biomarker of oxidative stress during major health problems such as cancer, etc.
Malondialdehyde (MDA) is the most widely used agent to estimate the extent of lipid peroxidation. Timely diagnosis of the condition followed by supplementation with antioxidants like beta-carotene, pro-vitamin A, vitamin A, vitamin C, vitamin E, lipoic acid, zinc, selenium, and spirulina can prevent potentially malignant disorders.
MDA is a lipid peroxidation marker
BC, Breast Cancer: Click to Expand ⟱
Breast Cancer
Scientific Papers found: Click to Expand⟱
301- ALA,  PacT,  doxoR,    Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities: a randomized controlled trial in breast cancer patients
- Human, BC, NA
BNP↓, TNF-α↓, MDA↓, NeuroT↓,
5898- CAR,    Carvacrol-induced apoptosis via tumor suppressor gene activation and oxidative stress modulation in a rat model of breast cancer
- in-vivo, BC, NA
*lipid-P↓, *MDA↓, *antiOx↑, *Inflam↑, RenoP↑, hepatoP↑, *ALAT↓, AST↓, creat↓, chemoPv↑, Cyt‑c↑, FADD↑, P53↑,
1251- RT,  OLST,    Rutin and orlistat produce antitumor effects via antioxidant and apoptotic actions
- in-vitro, BC, MCF-7 - in-vitro, PC, PANC1 - in-vivo, NA, NA
TumVol↓, *CEA↓, *FASN↓, *ROS↓, *MDA↓, *GSH↑, Apoptosis↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

MDA↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   Cyt‑c↑, 1,   FADD↑, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Migration ⓘ

NeuroT↓, 1,  

Immune & Inflammatory Signaling ⓘ

TNF-α↓, 1,  

Hormonal & Nuclear Receptors ⓘ

BNP↓, 1,  

Clinical Biomarkers ⓘ

AST↓, 1,   creat↓, 1,  

Functional Outcomes ⓘ

chemoPv↑, 1,   hepatoP↑, 1,   RenoP↑, 1,   TumVol↓, 1,  
Total Targets: 14

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   GSH↑, 1,   lipid-P↓, 1,   MDA↓, 2,   ROS↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   FASN↓, 1,  

Migration ⓘ

CEA↓, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   CEA↓, 1,  
Total Targets: 11

Scientific Paper Hit Count for: MDA, Serum malondialdehyde
1 Alpha-Lipoic-Acid
1 Paclitaxel
1 doxorubicin
1 Carvacrol
1 Rutin
1 Orlistat
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:570  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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