NADPH/NADP+ Cancer Research Results

NADPH/NADP+, NADPH/NADP+ ratio: Click to Expand ⟱
Source:
Type:
The NADPH/NADP+ ratio is a crucial indicator of cellular redox status and has been implicated in various diseases, including cancer. NADPH (Nicotinamide adenine dinucleotide phosphate) is a reducing agent that plays a central role in maintaining the balance of redox reactions within cells. In cancer cells, the NADPH/NADP+ ratio is often altered.
BC, Breast Cancer: Click to Expand ⟱
Breast Cancer
Scientific Papers found: Click to Expand⟱
374- AgNPs,    Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
ER Stress↑, DNAdam↑, ROS↑, Apoptosis↑, GSH/GSSG↓, NADPH/NADP+↓, TumCG↓, UPR↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

GSH/GSSG↓, 1,   NADPH/NADP+↓, 1,   ROS↑, 1,  

Cell Death ⓘ

Apoptosis↑, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↑, 1,   UPR↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: NADPH/NADP+, NADPH/NADP+ ratio
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:625  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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