G9a Cancer Research Results

G9a, G9a: Click to Expand ⟱
Source:
Type: enzyme
G9a is a histone methyltransferase enzyme that plays a crucial role in various cellular processes, including gene expression, DNA repair, and cell cycle regulation.
G9a has been found to be overexpressed in various types of cancer, including breast, lung, colon, and prostate cancer. This overexpression is often associated with poor prognosis and reduced survival rates.
BC, Breast Cancer: Click to Expand ⟱
Breast Cancer
Scientific Papers found: Click to Expand⟱
3426- TQ,    Thymoquinone-Induced Reactivation of Tumor Suppressor Genes in Cancer Cells Involves Epigenetic Mechanisms
- in-vitro, BC, MDA-MB-468 - in-vitro, AML, JK
UHRF1↓, DNMT1↓, DNMT3A↓, DNMTs↓, HDAC1↓, HDAC4↓, HDAC↓, DLC1↑, PPARγ↑, FOXO↑, TET2↑, CYP1B1↑, G9a↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

PPARγ↑, 1,  

DNA Damage & Repair ⓘ

CYP1B1↑, 1,   DNMT1↓, 1,   DNMT3A↓, 1,   DNMTs↓, 1,   G9a↓, 1,   UHRF1↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

FOXO↑, 1,   HDAC↓, 1,   HDAC1↓, 1,   HDAC4↓, 1,  

Migration ⓘ

DLC1↑, 1,  

Drug Metabolism & Resistance ⓘ

TET2↑, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: G9a, G9a
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:832  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page