Apoptosis Cancer Research Results

Apoptosis, Apoptosis: Click to Expand ⟱
Source:
Type: type of cell death
Situation in which a cell actively pursues a course toward death upon receiving certain stimuli.
Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die.
BC, Breast Cancer: Click to Expand ⟱
Breast Cancer
Scientific Papers found: Click to Expand⟱
1338- AG,    The Modulatory Properties of Astragalus membranaceus Treatment on Triple-Negative Breast Cancer: An Integrated Pharmacological Method
- in-vitro, BC, NA
TumCI↓, Apoptosis↑, Symptoms↓, PIK3CA↓, Akt↓, Bcl-2↓,
1000- AG,  5-FU,    Characterization and anti-tumor bioactivity of astragalus polysaccharides by immunomodulation
- vitro+vivo, BC, 4T1
TumCG↓, TumCCA↑, Apoptosis↑, *IL2↑, *TNF-α↑, *IFN-γ↑,
4417- AgNPs,    Caffeine-boosted silver nanoparticles target breast cancer cells by triggering oxidative stress, inflammation, and apoptotic pathways
- in-vitro, BC, MDA-MB-231
ROS↑, MDA↑, COX2↑, IL1β↑, TNF-α↑, GSH↓, Cyt‑c↑, Casp3↑, BAX↑, Bcl-2↓, LDH↓, cycD1/CCND1↓, CDK2↓, TumCCA↑, mt-Apoptosis↑,
4416- AgNPs,    Efficacy of curcumin-synthesized silver nanoparticles on MCF-7 breast cancer cells
- in-vitro, BC, MCF-7
TumCMig↓, Apoptosis↑, BAX↑, P53↑, Bcl-2↓,
4406- AgNPs,    Silver nanoparticles achieve cytotoxicity against breast cancer by regulating long-chain noncoding RNA XLOC_006390-mediated pathway
- in-vitro, BC, MCF-7 - in-vitro, BC, T47D - in-vitro, BC, MDA-MB-231
TumCD↑, other↓, P53↑, TumCCA↑, Apoptosis↑, ChemoSen↑, tumCV↓, γH2AX↑, SOX4↓,
4563- AgNPs,  Rad,    Silver nanoparticles enhance neutron radiation sensitivity in cancer cells: An in vitro study
- in-vitro, BC, MCF-7 - in-vitro, Ovarian, SKOV3 - in-vitro, GBM, U87MG - in-vitro, Melanoma, A431
RadioS↑, ROS↑, TumCCA↑, Apoptosis↑, ER Stress↑,
4559- AgNPs,    Anticancer activity of biogenerated silver nanoparticles: an integrated proteomic investigation
- in-vitro, BC, SkBr3 - in-vitro, CRC, HT-29 - in-vitro, CRC, HCT116 - in-vitro, Colon, Caco-2
MMP2↓, MMP9↓, ROS↑, TumAuto↑, Apoptosis↑, ER Stress↑,
5145- AgNPs,    Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells
- in-vitro, BC, MCF-7 - in-vitro, BC, T47D
Bacteria↓, Apoptosis↑, ER Stress↑, UPR↑, PERK↑, IRE1↑, ATF6↑, ATF4↑, CHOP↑, Casp9↑, Casp7↑, Mcl-1↓, XIAP↓, PARP↝, selectivity↑,
336- AgNPs,  PDT,    Photodynamic ability of silver nanoparticles in inducing cytotoxic effects in breast and lung cancer cell lines
- in-vitro, BC, MCF-7
Apoptosis↑,
374- AgNPs,    Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
ER Stress↑, DNAdam↑, ROS↑, Apoptosis↑, GSH/GSSG↓, NADPH/NADP+↓, TumCG↓, UPR↑,
348- AgNPs,    Induction of p53 mediated mitochondrial apoptosis and cell cycle arrest in human breast cancer cells by plant mediated synthesis of silver nanoparticles from Bergenia ligulata (Whole plant)
- in-vitro, BC, MCF-7
Apoptosis↑, ROS↑, MMP↓, P53↑, BAX↑, cl‑Casp3↑,
349- AgNPs,    Insight into the molecular mechanism, cytotoxic, and anticancer activities of phyto-reduced silver nanoparticles in MCF-7 breast cancer cell lines
- in-vitro, BC, MCF-7
Apoptosis↑, ROS↑, CellMemb↑,
356- AgNPs,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF-7 - in-vitro, Bladder, HTB-22
Apoptosis↑, P53↑, iNOS↑, NF-kB↑, Bcl-2↓, ROS↑, SOD↑, TumCCA↑, eff↑, Catalase↑, other↑,
353- AgNPs,    The mechanism of cell death induced by silver nanoparticles is distinct from silver cations
- in-vitro, BC, SUM159
lipid-P↑, H2O2↑, ROS↑, Apoptosis↑,
377- AgNPs,    Anticancer Action of Silver Nanoparticles in SKBR3 Breast Cancer Cells through Promotion of Oxidative Stress and Apoptosis
- in-vitro, BC, SkBr3
ROS↑, Apoptosis↑, Bax:Bcl2↑, VEGF↑, Akt↓, PI3K↓, TAC↓, TOS↑, OSI↑, MDA↑, Casp3↑, Casp7↑,
376- AgNPs,    Antitumor activity of colloidal silver on MCF-7 human breast cancer cells
- in-vitro, BC, MCF-7
Apoptosis↑, LDH↓, SOD↑, DNAdam↑,
382- AgNPs,    Investigation the apoptotic effect of silver nanoparticles (Ag-NPs) on MDA-MB 231 breast cancer epithelial cells via signaling pathways
- in-vitro, BC, MDA-MB-231
Apoptosis↑, BAX↑, Bcl-2↓, P53↑, PTEN↑, hTERT/TERT↓, p‑ERK↓, cycD1/CCND1↓,
255- AL,    Allicin induces cell cycle arrest and apoptosis of breast cancer cells in vitro via modulating the p53 pathway
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
Apoptosis↑, P53↑, Casp3↑, P53↑, TPM4↓, TumCCA↑, THBS1↑,
297- ALA,    Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
- Review, BC, SkBr3 - Review, neuroblastoma, SK-N-SH - Review, AD, NA
PDH↑, TumCG↓, ROS↑, AMPK↑, EGR4↓, Half-Life↓, BioAv↝, *GSH↑, *IronCh↑, *ROS↓, *antiOx↑, *neuroP↑, *Ach↑, *lipid-P↓, *IL1β↓, *IL6↓, TumCP↓, FDG↓, Apoptosis↑, AMPK↑, mTOR↓, EGFR↓, TumCI↓, TumCMig↓, *memory↑, *BioAv↑, *BioAv↝, *other↓, *other↝, *Half-Life↓, *BioAv↑, *ChAT↑, *GlucoseCon↑,
298- ALA,  Rad,    Synergistic Tumoricidal Effects of Alpha-Lipoic Acid and Radiotherapy on Human Breast Cancer Cells via HMGB1
- in-vitro, BC, MDA-MB-231
Apoptosis↑, P53↑, p38↑, NF-kB↑, TumCCA↑,
260- ALA,    The effects of alpha-lipoic acid on breast of female albino rats exposed to malathion: Histopathological and immunohistochemical study
- in-vivo, BC, NA
PCNA↓, P53↓, Apoptosis↑, BAX↑,
1252- aLinA,    α-Linolenic acid induces apoptosis, inhibits the invasion and metastasis, and arrests cell cycle in human breast cancer cells by inhibiting fatty acid synthase
- in-vitro, BC, NA
FASN↓, Apoptosis↑, TumCI↓, TumMeta↓, TumCCA↑,
1078- And,    Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, HUVECs - in-vivo, BC, MCF-7 - in-vitro, BC, T47D - in-vitro, BC, BT549 - in-vitro, BC, MDA-MB-361
TumCP↓, COX2↓, *angioG↓, Cyt‑c↑, CREB2↓, cFos↓, NF-kB↓, HATs↓, cl‑Casp3↑, cl‑Casp9↑, Bax:Bcl2↑, Apoptosis↑, *toxicity↓,
1279- And,    Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7
Apoptosis↑, Bcl-2↓, BAX↑, ERα/ESR1↓, PI3K↓, mTOR↓,
2593- Api,    Apigenin promotes apoptosis of 4T1 cells through PI3K/AKT/Nrf2 pathway and improves tumor immune microenvironment in vivo
- in-vivo, BC, 4T1
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, MMP↑, ROS↑, p‑PI3K↓, PI3K↓, Akt↓, NRF2↓, AntiTum↑, OS↑,
1142- Ash,    Ashwagandha-Induced Programmed Cell Death in the Treatment of Breast Cancer
- Review, BC, MCF-7 - NA, BC, MDA-MB-231 - NA, Nor, HMEC
Apoptosis↑, ROS↑, DNAdam↑, OXPHOS↓, *ROS∅, Bcl-2↓, XIAP↓, survivin↓, DR5↑, IKKα↓, NF-kB↓, selectivity↑, *ROS∅, eff↓, Paraptosis↑,
1360- Ash,  immuno,    Withaferin A Increases the Effectiveness of Immune Checkpoint Blocker for the Treatment of Non-Small Cell Lung Cancer
- in-vitro, Lung, H1650 - in-vitro, Lung, A549 - in-vitro, CRC, HCT116 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
PD-L1↑, eff↓, ROS↑, ER Stress↑, Apoptosis↑, BAX↑, Bak↑, BAD↑, Bcl-2↓, XIAP↓, survivin↓, cl‑PARP↑, CHOP↑, p‑eIF2α↑, ICD↑, eff↑,
1367- Ash,    An anti-cancerous protein fraction from Withania somnifera induces ROS-dependent mitochondria-mediated apoptosis in human MDA-MB-231 breast cancer cells
- in-vitro, BC, MDA-MB-231
Apoptosis↑, ROS↑, Bax:Bcl2↑, MMP↓, Casp3↑, TumCCA↑,
1174- Ash,    Withaferin A Suppresses Estrogen Receptor-α Expression in Human Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vivo, BC, MDA-MB-231 - in-vitro, BC, T47D
p‑P53↑, Apoptosis↑, ERα/ESR1↓,
4821- ASTX,    Astaxanthin Reduces Stemness Markers in BT20 and T47D Breast Cancer Stem Cells by Inhibiting Expression of Pontin and Mutant p53
- in-vitro, BC, SkBr3 - in-vitro, BC, BT20 - in-vitro, BC, T47D
Apoptosis↑, CSCs↓, OCT4↓, Nanog↓, TumCP↓,
4819- ASTX,    Astaxanthin Induces Apoptosis in MCF-7 Cells through a p53-Dependent Pathway
- in-vitro, BC, MCF-7
antiOx↑, AntiTum↑, TumCD↑, P53↑, P21↑, Apoptosis↑, Dose↝, Casp3↑,
4978- ATV,  Rad,    Atorvastatin Sensitizes Breast and Lung Cancer Cells to Ionizing Radiation
- in-vitro, BC, A549
Apoptosis↑, RadioS↑, TumCP↓, ROS↑,
1053- Ba,  docx,    Baicalin, a Potent Inhibitor of NF-κB Signaling Pathway, Enhances Chemosensitivity of Breast Cancer Cells to Docetaxel and Inhibits Tumor Growth and Metastasis Both In Vitro and In Vivo
- in-vivo, BC, 4T1
TumCP↓, Apoptosis↑, ROS↑, Bax:Bcl2↑, NF-kB↓, ChemoSen↑, survivin↓,
5248- Ba,  BA,  doxoR,    Baicalin and Baicalein Enhance Cytotoxicity, Proapoptotic Activity, and Genotoxicity of Doxorubicin and Docetaxel in MCF-7 Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, Nor, HUVECs
toxicity↝, ChemoSen↑, selectivity↑, Apoptosis↑, necrosis↑, MMP↓, DNAdam↑, cl‑PARP↑, MRP1↓, Bcl-2↓, hepatoP↑, cardioP↑, BioAv↝,
2599- Ba,    Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
TumCP↓, Apoptosis↑, p‑Akt↓, p‑mTOR↓, NF-kB↓, p‑IKKα↓, IKKα↑, PI3K↓, MMP↓, TumAuto↑, TumVol↓, TumW↓,
5543- BBM,    Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo
- in-vivo, Lung, B16-F10 - vitro+vivo, Lung, A549 - in-vitro, BC, MDA-MB-231
BioAv↓, Half-Life↓, eff↑, TumMeta↓, TumCP↓, TumCG↓, Apoptosis↑, TumCCA↑, MMP2↓, MMP9↓, VEGF↓, Bcl-2↓, eff↑, EPR↑,
1389- BBR,  Lap,    Berberine reverses lapatinib resistance of HER2-positive breast cancer cells by increasing the level of ROS
- in-vitro, BC, BT474 - in-vitro, BC, AU-565
ChemoSen↑, Apoptosis↑, ROS↑, NRF2↓,
2711- BBR,    Berberine inhibits the progression of breast cancer by regulating METTL3-mediated m6A modification of FGF7 mRNA
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
TumCP↓, TumCI↓, TumCMig↓, Apoptosis↑, FGF↓, IGFBP3↑,
1473- BCA,  SFN,    An Insight on Synergistic Anti-cancer Efficacy of Biochanin A and Sulforaphane Combination Against Breast Cancer
- in-vitro, BC, MCF-7
eff↑, ROS↑, other↑, ERK↓, Apoptosis↑,
5639- BCA,    Biochanin A Induces Apoptosis in MCF-7 Breast Cancer Cells through Mitochondrial Pathway and Pi3K/AKT Inhibition
- in-vitro, BC, NA
TumCP↓, ROS↑, Apoptosis↑, Bcl-2↓, p‑PI3K↓, p‑Akt↓, BAX↑, Casp3↑, Casp9↑, Cyt‑c↑, CycD3↓, CycB/CCNB1↓, CDK1↓, CDK2↓, CDK4↓, P21↑, p27↑, P53↑, tumCV↓, PI3K↓, Akt↓,
5510- bemA,    Combined inhibition of ACLY and CDK4/6 reduces cancer cell growth and invasion
- in-vitro, BC, MDA-MB-231 - in-vitro, PC, NA
eff↑, Apoptosis↑, TumCI↓, ACLY↓, LDL↓, eff↑, TumCP↓,
2723- BetA,    Betulinic acid and oleanolic acid modulate CD81 expression and induce apoptosis in triple-negative breast cancer cells through ROS generation
- in-vitro, BC, MDA-MB-231
Apoptosis↑, tumCV↓, ROS↑,
2727- BetA,    Betulinic acid in the treatment of breast cancer: Application and mechanism progress
- Review, BC, NA
mt-ROS↑, Sp1/3/4↓, TumMeta↓, GlucoseCon↓, NF-kB↓, ChemoSen↑, chemoP↑, m-Apoptosis↑, TOP1↓,
724- Bor,    Does Boric Acid Inhibit Cell Proliferation on MCF-7 and MDA-MB-231 Cells in Monolayer and Spheroid Cultures by Using Apoptosis Pathways?
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7
Apoptosis↑, Casp3↝, Casp8↝, Casp9↝,
1424- Bos,    Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells
- in-vitro, BC, T47D - in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
tumCV↓, Apoptosis↑, cl‑Casp8↑, cl‑Casp9↑, cl‑PARP↑,
5870- CA,    Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen‐Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells
- vitro+vivo, BC, T47D - in-vitro, BC, MCF-7
ROS↑, cJun↑, p38↑, eff↓, TumCP↓, glucose↓, Apoptosis↑, BAX↑, PARP↑, Bcl-2↓, TumCG↑, Ki-67↓, STAT3↓, PI3K↓, Akt↓, mTOR↓,
5874- CA,    Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells
- vitro+vivo, BC, T47D - in-vitro, BC, MCF10
AntiTum↓, ROS↑, cJun↑, p‑p38↑, Apoptosis↑, ROS↑, eff↑, TumCP↓, glucose↓, BAX↑, PARP↑, Bcl-2↓, eff↓, Ki-67↓, toxicity↝, STAT3↓, PI3K↓, Akt↓, mTOR↓,
1262- CAP,    Capsaicin Inhibits Proliferation and Induces Apoptosis in Breast Cancer by Down-Regulating FBI-1-Mediated NF-κB Pathway
- vitro+vivo, BC, NA
FBI-1↓, Ki-67↓, Bcl-2↓, survivin↓, BAX↑, Casp3↑, TumCP↓, Apoptosis↑,
5764- CAPE,    Caffeic Acid Phenethyl Ester (CAPE), Derived from a Honeybee Product Propolis, Exhibits a Diversity of Anti-tumor Effects in Preclinical Models of Human Breast Cancer
- vitro+vivo, BC, MCF-7 - NA, BC, MDA-MB-231
TumCG↓, TumCCA↑, Apoptosis↑, NF-kB↓, MDR1↓, VEGF↓, angioG↓,
5882- CAR,    Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breast Cancer Cells
- in-vitro, BC, MCF-7
tumCV↓, TumCCA↑, pRB↓, cycD1/CCND1↓, CDK4↓, CDK6↓, PI3K↓, p‑Akt↓, Apoptosis↑, Bcl-2↓, BAX↑,

Showing Research Papers: 1 to 50 of 143
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 143

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   Catalase↑, 1,   GSH↓, 1,   GSH/GSSG↓, 1,   H2O2↑, 1,   ICD↑, 1,   lipid-P↑, 1,   MDA↑, 2,   NADPH/NADP+↓, 1,   NRF2↓, 2,   OSI↑, 1,   OXPHOS↓, 1,   ROS↑, 23,   mt-ROS↑, 1,   SOD↑, 2,   TAC↓, 1,   TOS↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 4,   MMP↑, 1,   XIAP↓, 3,  

Core Metabolism/Glycolysis ⓘ

ACLY↓, 1,   AMPK↑, 2,   FASN↓, 1,   FBI-1↓, 1,   FDG↓, 1,   glucose↓, 2,   GlucoseCon↓, 1,   LDH↓, 2,   LDL↓, 1,   PDH↑, 1,   PIK3CA↓, 1,  

Cell Death ⓘ

Akt↓, 6,   p‑Akt↓, 3,   Apoptosis↑, 48,   m-Apoptosis↑, 1,   mt-Apoptosis↑, 1,   BAD↑, 1,   Bak↑, 1,   BAX↑, 12,   Bax:Bcl2↑, 4,   Bcl-2↓, 15,   Casp3↑, 7,   Casp3↝, 1,   cl‑Casp3↑, 2,   Casp7↑, 2,   Casp8↝, 1,   cl‑Casp8↑, 1,   Casp9↑, 2,   Casp9↝, 1,   cl‑Casp9↑, 2,   Cyt‑c↑, 3,   DR5↑, 1,   hTERT/TERT↓, 1,   iNOS↑, 1,   Mcl-1↓, 1,   necrosis↑, 1,   p27↑, 1,   p38↑, 2,   p‑p38↑, 1,   Paraptosis↑, 1,   survivin↓, 4,   TumCD↑, 2,  

Kinase & Signal Transduction ⓘ

Sp1/3/4↓, 1,  

Transcription & Epigenetics ⓘ

cJun↑, 2,   HATs↓, 1,   other↓, 1,   other↑, 2,   pRB↓, 1,   tumCV↓, 5,  

Protein Folding & ER Stress ⓘ

ATF6↑, 1,   CHOP↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 5,   IRE1↑, 1,   PERK↑, 1,   UPR↑, 2,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 2,  

DNA Damage & Repair ⓘ

DNAdam↑, 4,   P53↓, 1,   P53↑, 10,   p‑P53↑, 1,   PARP↑, 2,   PARP↝, 1,   cl‑PARP↑, 3,   PCNA↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

CDK1↓, 1,   CDK2↓, 2,   CDK4↓, 2,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 3,   CycD3↓, 1,   P21↑, 2,   TumCCA↑, 12,  

Proliferation, Differentiation & Cell State ⓘ

cFos↓, 1,   CREB2↓, 1,   CSCs↓, 1,   ERK↓, 1,   p‑ERK↓, 1,   FGF↓, 1,   IGFBP3↑, 1,   mTOR↓, 4,   p‑mTOR↓, 1,   Nanog↓, 1,   OCT4↓, 1,   PI3K↓, 8,   p‑PI3K↓, 2,   PTEN↑, 1,   STAT3↓, 2,   TOP1↓, 1,   TPM4↓, 1,   TumCG↓, 5,   TumCG↑, 1,  

Migration ⓘ

Ki-67↓, 3,   MMP2↓, 2,   MMP9↓, 2,   SOX4↓, 1,   THBS1↑, 1,   TumCI↓, 6,   TumCMig↓, 4,   TumCP↓, 14,   TumMeta↓, 3,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   ATF4↑, 1,   EGFR↓, 1,   EGR4↓, 1,   EPR↑, 1,   VEGF↓, 2,   VEGF↑, 1,  

Barriers & Transport ⓘ

CellMemb↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   COX2↑, 1,   IKKα↓, 1,   IKKα↑, 1,   p‑IKKα↓, 1,   IL1β↑, 1,   NF-kB↓, 6,   NF-kB↑, 2,   PD-L1↑, 1,   TNF-α↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,   ERα/ESR1↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↝, 2,   ChemoSen↑, 5,   Dose↝, 1,   eff↓, 4,   eff↑, 8,   Half-Life↓, 2,   MDR1↓, 1,   MRP1↓, 1,   RadioS↑, 2,   selectivity↑, 3,  

Clinical Biomarkers ⓘ

EGFR↓, 1,   ERα/ESR1↓, 2,   hTERT/TERT↓, 1,   Ki-67↓, 3,   LDH↓, 2,   PD-L1↑, 1,  

Functional Outcomes ⓘ

AntiTum↓, 1,   AntiTum↑, 2,   cardioP↑, 1,   chemoP↑, 1,   hepatoP↑, 1,   OS↑, 1,   Symptoms↓, 1,   toxicity↝, 2,   TumVol↓, 1,   TumW↓, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 170

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   GSH↑, 1,   lipid-P↓, 1,   ROS↓, 1,   ROS∅, 2,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis ⓘ

GlucoseCon↑, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 1,   other↓, 1,   other↝, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,  

Immune & Inflammatory Signaling ⓘ

IFN-γ↑, 1,   IL1β↓, 1,   IL2↑, 1,   IL6↓, 1,   TNF-α↑, 1,  

Synaptic & Neurotransmission ⓘ

ChAT↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 2,   BioAv↝, 1,   Half-Life↓, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  

Functional Outcomes ⓘ

memory↑, 1,   neuroP↑, 1,   toxicity↓, 1,  
Total Targets: 24

Scientific Paper Hit Count for: Apoptosis, Apoptosis
17 Silver-NanoParticles
8 Magnetic Fields
6 Thymoquinone
5 Carvacrol
4 Ashwagandha(Withaferin A)
4 doxorubicin
4 Curcumin
4 Luteolin
4 Resveratrol
4 Quercetin
4 salinomycin
3 Radiotherapy/Radiation
3 Alpha-Lipoic-Acid
3 Baicalein
3 Sulforaphane (mainly Broccoli)
3 Chlorogenic acid
3 Chlorophyllin
3 Paclitaxel
3 Garcinol
3 Graviola
2 Astragalus
2 Andrographis
2 Apigenin (mainly Parsley)
2 Astaxanthin
2 Berberine
2 Biochanin A
2 Betulinic acid
2 Carnosic acid
2 chitosan
2 EGCG (Epigallocatechin Gallate)
2 Fisetin
2 Gold NanoParticles
2 Honokiol
2 Lycopene
2 Phenethyl isothiocyanate
2 Piperlongumine
2 Rutin
2 Vitamin C (Ascorbic Acid)
1 5-fluorouracil
1 Photodynamic Therapy
1 Allicin (mainly Garlic)
1 alpha Linolenic acid
1 immunotherapy
1 Atorvastatin
1 Docetaxel
1 Baicalin
1 Berbamine
1 Lapatinib
1 bempedoic acid
1 Boron
1 Boswellia (frankincense)
1 Capsaicin
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Thymol-Thymus vulgaris
1 Beta‐Lapachone
1 Chrysin
1 Coenzyme Q10
1 Copper and Cu NanoParticles
1 Electrical Pulses
1 methylseleninic acid
1 Date Fruit Extract
1 diet Methionine-Restricted Diet
1 Ellagic acid
1 Folic Acid, Vit B9
1 Ferulic acid
1 Gallic acid
1 carboplatin
1 Gambogic Acid
1 Genistein (soy isoflavone)
1 HydroxyCitric Acid
1 tamoxifen
1 HydroxyTyrosol
1 Licorice
1 Metformin
1 Chemotherapy
1 Naringin
1 Oleuropein
1 Phenylbutyrate
1 Parthenolide
1 Rosmarinic acid
1 Orlistat
1 Vorinostat
1 Selenium NanoParticles
1 Selenite (Sodium)
1 Ursolic acid
1 Urolithin
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:4  Cells:%  prod#:%  Target#:14  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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