ITGB1 Cancer Research Results

ITGB1, Integrin beta-1: Click to Expand ⟱

Source:

Type:

ITGB1, also known as Integrin beta-1 or β1-integrin, is a protein that plays a crucial role in cell adhesion, migration, and signaling. It is a transmembrane receptor that interacts with various extracellular matrix proteins, such as collagen, laminin, and fibronectin.
ITGB1 is overexpressed in: breast, lung, colon, prostate, CRC, ovarian, pancreatic, gastric, esophageal, melanoma, GBM

BC, Breast Cancer: Click to Expand ⟱

Breast Cancer

Scientific Papers found: Click to Expand⟱

756-

Bor,

Evaluation of Boric Acid Treatment on microRNA‐127‐5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells

in-vitro,

BC,

MCF-7

45.69 mM

However, it cannot be said that it improves the metastasis properties of breast cancer stem cells.

COL1A1↓, Vim↓, miR-127-5p↑, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑,

736-

Bor,

Evaluation of Boric Acid Treatment on microRNA-127-5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells

in-vitro,

BC,

MCF-7

45.69 mM

miR-126↑, COL1A1↓, Vim↓, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑, miR-127-5p↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

miR-127-5p↑, 2,

Migration ⓘ

CDH1↑, 2, COL1A1↓, 2, ITGA5↑, 2, ITGB1↑, 2, LAMA5↑, 2, Snail↑, 2, Vim↓, 2, Zeb1↑, 2,

Angiogenesis & Vasculature ⓘ

miR-126↑, 1,
Total Targets: 10

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: ITGB1, Integrin beta-1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells